Evidence map›Paper›PMID 24115373›Full record

Trial reportObesity (Silver Spring, Md.)2014

Fasting plasma adropin concentrations correlate with fat consumption in human females.

Marie-Pierre St-Onge, Ari Shechter, Julie Shlisky, Charmaine S Tam, Su Gao, Eric Ravussin, Andrew A Butler

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02835261 (Impact of Sleep Restriction on Cardiometabolic Risk Factors in Pre vs Postmenopausal Women), which is not on this map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02835261 nacompletednot on this mapstarted 2016, after this paper: background citation

Impact of Sleep Restriction on Cardiometabolic Risk Factors in Pre vs Postmenopausal Women

TypeinterventionalSponsorColumbia UniversityRan2016 to 2021Enrolled54ConditionsSleep, Cardiovascular Disease, ObesityArmsSleep Restriction
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Adropin: A New Regulator of Testicular Function-What Do We Know So Far?International journal of molecular sciences · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Observational
  10. Article
  11. Review
  12. Article
  13. Article
  14. Serum Adropin Levels Are Elevated in Patients With Hyperthyroidism.International journal of endocrinology · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marie-Pierre St-OngeNew York Obesity Nutrition Research Center, St. Luke's/Roosevelt Hospital and College of Physicians and Surgeons, Columbia University, New York, 10025, USA.
Ari Shechter
Julie Shlisky
Charmaine S Tam
Su Gao
Eric Ravussin
Andrew A Butler

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024156 · NCRR · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2006 to 2011
$53.0M
RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2005 to 2026
$26.5M
Fat Cell Size, Overfeeding & Ectopic FatR01DK060412 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI RAVUSSIN, ERIC · 2001 to 2011
$5.4M
OBESITY RESEARCH CENTER TRAINING PROGRAMT32DK007559 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI DYMPNA GALLAGHER · 1989 to 2026
$4.3M
Sleep deprivation and energy balanceR01HL091352 · NHLBI · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI ST-ONGE, MARIE-PIERRE · 2008 to 2011
$2.7M
NCRR NIH HHS 1 UL1RR024156-03NCRR NIH HHS UL1 RR024156NHLBI NIH HHS 1R01HL091352-01A1NHLBI NIH HHS 1R01HL091352-01S1NHLBI NIH HHS R01 HL091352NIDDK NIH HHS 2P30 DK072476NIDDK NIH HHS P30 DK026687NIDDK NIH HHS P30 DK072476NIDDK NIH HHS P30 DK-26687NIDDK NIH HHS R01 DK060412NIDDK NIH HHS T32 DK007559
6 · The paper itself

Abstract

objectiveThis study investigated whether plasma adropin concentrations are influenced by sleep restriction and correlate with dietary preferences.

methodsPlasma adropin concentrations were measured by ELISA using samples from a study that investigated feeding behavior in sleep deprived lean (body mass index 22-26 kg/m(2) ) men and women aged 30-45 y. Sleep (habitual or restricted to 4h/night) and diet were controlled during a 4-day inpatient period. On day 5, food was self-selected (FS). Adropin was measured on day 4 in samples collected throughout the day, and then after an overnight fast at 0730 on days 5 (Pre-FS) and 6 (Post-FS).

resultsPlasma adropin concentrations were not affected by sleep restriction. However, circulating adropin concentrations correlated with food selection preferences in women, irrespective of sleep status. Pre-FS adropin correlated positively with fat intake (total fat, r = 0.867, P < 0.05; saturated fat, r = 0.959, P < 0.01) and negatively with carbohydrate intake (r = -0.894, P < 0.05) as a percent total energy. Post-FS adropin correlated with total (r = 0.797, P < 0.05) and saturated fat intake (r = 0.945, P < 0.01), and negative with total carbohydrate intake (r = -0.929, P < 0.01). Pre-FS adropin also correlated with fat intake in kcal adjusted for body size (total fat, r = 0.852, P < 0.05; saturated fat, r = 0.927, P < 0.01).

conclusionsPlasma adropin concentrations correlate with fat consumption in women.

Indexed as

Dietary FatsAdultBlood ProteinsCross-Over StudiesDietary CarbohydratesEatingFastingFeeding BehaviorFemaleFood PreferencesHumansInpatientsIntercellular Signaling Peptides and ProteinsMaleMiddle AgedPeptidesBlood ProteinsDietary CarbohydratesDietary FatsEnho protein, humanIntercellular Signaling Peptides and ProteinsPeptides

Identifiers

PMID24115373
PMCPMC3968187

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.