Evidence map›Paper›PMID 24114545›Full record

ArticleInvestigative ophthalmology & visual science2013

Rapid and reliable assessment of the contrast sensitivity function on an iPad.

Michael Dorr, Luis A Lesmes, Zhong-Lin Lu, Peter J Bex

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02177669 (Test-Retest Variability of Quick Contrast Sensitivity Function Testing), which is not on this map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02177669 completednot on this mapstarted 2014, after this paper: background citation

Test-Retest Variability of Quick Contrast Sensitivity Function Testing

TypeobservationalSponsorNova Southeastern UniversityRan2014 to 2016Enrolled100ConditionsHealthyArmsquick Contrast Sensitivity Function test
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 111 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Validation and evaluation of visual acuity and contrast sensitivity with a new digital device: OPTOTAB®.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Article
  7. OCT-Based Retina Assessment Reflects Visual Impairment in Multiple Sclerosis.Investigative ophthalmology & visual science · 2025
    Article
  8. The importance of assessing vision in falls management: A narrative review.Optometry and vision science : official publication of the American Academy of Optometry · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Optical coherence tomography angiography in diabetic retinopathy.Progress in retinal and eye research · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Michael DorrSchepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
Luis A Lesmes
Zhong-Lin Lu
Peter J Bex
Massachusetts Eye and Ear Infirmary · USThe Ohio State University · US

Funding

The Functions and Mechanisms of Perceptual LearningR01EY017491 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI DOSHER, BARBARA A., LU, ZHONG-LIN · 2006 to 2023
$6.1M
Efficient Assessment of Visual Deficits and Rehabilitation Methods in AmblyopiaR01EY021553 · NEI · OHIO STATE UNIVERSITY · PI LU, ZHONG-LIN · 2012 to 2016
$2.1M
Enhancement of Dynamic Media for Visually-Impaired PeopleR01EY019281 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI BEX, PETER JOHN · 2009 to 2012
$1.9M
Psychophysical Correlates of Neurodegeneration in GlaucomaR01EY018664 · NEI · SCHEPENS EYE RESEARCH INSTITUTE · PI BEX, PETER JOHN · 2009 to 2012
$1.9M
NEI NIH HHS EY017491NEI NIH HHS EY018664NEI NIH HHS EY019281NEI NIH HHS R01 EY017491NEI NIH HHS R01 EY018664NEI NIH HHS R01 EY019281NEI NIH HHS R01 EY021553
6 · The paper itself

Abstract

purposeLetter acuity, the predominant clinical assessment of vision, is relatively insensitive to slow vision loss caused by eye disease. While the contrast sensitivity function (CSF) has demonstrated the potential to monitor the slow progress of blinding eye diseases, current tests of CSF lack the reliability or ease-of-use to capture changes in vision timely. To improve the current state of home testing for vision, we have developed and validated a computerized adaptive test on a commercial tablet device (iPad) that provides an efficient and easy-to-use assessment of the CSF.

methodsWe evaluated the reliability, accuracy, and flexibility of tablet-based CSF assessment. Repeated tablet-based assessments of the spatial CSF, obtained from four normally-sighted observers, which each took 3 to 5 minutes, were compared to measures obtained on CRT-based laboratory equipment; additional tablet-based measures were obtained from six subjects under three different luminance conditions.

resultsA Bland-Altman analysis demonstrated that tablet-based assessment was reliable for estimating sensitivities at specific spatial frequencies (coefficient of repeatability 0.14-0.40 log units). The CRT- and tablet-based results demonstrated excellent agreement with absolute mean sensitivity differences <0.05 log units. The tablet-based test also reliably identified changes in contrast sensitivity due to different luminance conditions.

conclusionsWe demonstrate that CSF assessment on a mobile device is indistinguishable from that obtained with specialized laboratory equipment. We also demonstrate better reliability than tests used currently for clinical trials of ophthalmic therapies, drugs, and devices.

Indexed as

Computers, HandheldContrast SensitivityAdultDiagnosis, Computer-AssistedFemaleHumansMaleMiddle AgedReproducibility of ResultsSensitivity and SpecificityVision DisordersVision TestsYoung Adultadaptive testingcontrast sensitivitytelemonitoring

Identifiers

PMID24114545
PMCPMC4589140
OpenAlexW1982799089

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.