ArticleCell stress & chaperones2014
Seasonal variation in expression pattern of genes under HSP70 : Seasonal variation in expression pattern of genes under HSP70 family in heat- and cold-adapted goats (Capra hircus).
Article in Cell stress & chaperones, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
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48 citing papers in PubMed.
- Mapping genomic adaptation to environmental heterogeneity in Indian native goat populations through landscape genomics.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- HSPA6 is induced by RIG-I-like receptors and negatively regulates type-I interferon signaling.Cellular and molecular life sciences : CMLS · 2026Article
- Climate change and the emergence of Rift Valley fever virus: a pathological and environmental study of sheep jaundice in Egyptian slaughterhouses.BMC veterinary research · 2025Article
- Thermal Stress Response Profiling Reveals Adaptive Advantages of Indigenous Hercegovačka and Dubska Pramenka Sheep.Animals : an open access journal from MDPI · 2025Article
- Genomic advancements in goat breeding: enhancing productivity, disease resistance, and sustainability in India's rural economy.Mammalian genome : official journal of the International Mammalian Genome Society · 2025Review
- Genetic variation in the bovine heat shock protein gene in Indonesian Bali cattle (Open veterinary journal · 2025Article
- Climate resilience in goats: a comprehensive review of the genetic basis for adaptation to varied climatic conditions.Mammalian genome : official journal of the International Mammalian Genome Society · 2025Review
- Methionine Modulates the Growth and Development of Heat-Stressed Dermal Papilla Cells via the Wnt/β-Catenin Signaling Pathway.International journal of molecular sciences · 2025Article
- Molecular Characterization and Seasonal Variation in Expression of HSP70.1 Gene in Gangatiri Cattle and Its Comparison with Buffalo.Biochemical genetics · 2025Article
- The effect of heat stress on the hindgut microbiota and metabolites of Simmental heifers.Frontiers in microbiology · 2025Article
- Exploring transcriptomic mechanisms underlying pulmonary adaptation to diverse environments in Indian rams.Molecular biology reports · 2024Article
- Effects of Heat Stress on Goat Production and Mitigating Strategies: A Review.Animals : an open access journal from MDPI · 2024Review
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- The Effects of Housing on Growth, Immune Function and Antioxidant Status of Young Female Lambs in Cold Conditions.Animals : an open access journal from MDPI · 2024Article
- Comparative hemolymph proteomic analyses of the freezing and resistance-freezing Ostrinia furnacalis (Guenée).Scientific reports · 2024Article
- Impact of trypanosomiasis on male camel infertility.Frontiers in veterinary science · 2024Article
- Whole genome sequencing identified genomic diversity and candidated genes associated with economic traits in Northeasern Merino in China.Frontiers in genetics · 2024Article
- Hungarian indigenous Tsigai, a promising breed for excellent heat tolerance and immunity.Saudi journal of biological sciences · 2023Article
- Stress Factors and Their Effects on Productivity in Sheep.Animals : an open access journal from MDPI · 2023Review
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Authors and funding
11 authors.
Funding
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Abstract
Heat shock protein 70 (HSP70) is one of the most abundant and best characterized heat shock protein family that consists of highly conserved stress proteins, expressed in response to stress, and plays crucial roles in environmental stress tolerance and adaptation. The present study was conducted to identify major types of genes under the HSP70 family and to quantify their expression pattern in heat- and cold-adapted Indian goats (Capra hircus) with respect to different seasons. Five HSP70 gene homologues to HSPA8, HSPA6, HSPA1A, HSPA1L, and HSPA2 were identified by gene-specific primers. The cDNA sequences showed high similarity to other mammals, and proteins have an estimated molecular weight of around 70 kDa. The expression of HSP70 genes was observed during summer and winter. During summer, the higher expression of HSPA8, HSPA6, and HSPA1A was observed, whereas the expression levels of HSPA1L and HSPA2 were found to be lower. It was also observed that the expression of HSPA1A and HSPA8 was higher during winter in both heat- and cold-adapted goats but downregulates in case of other HSPs. Therefore, both heat and cold stress induced the overexpression of HSP70 genes. An interesting finding that emerged from the study is the higher expression of HSP70 genes in cold-adapted goats during summer and in heat-adapted goats during winter. Altogether, the results indicate that the expression pattern of HSP70 genes is species- and breed-specific, most likely due to variations in thermal tolerance and adaptation to different climatic conditions.
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