Evidence map›Paper›PMID 24113529›Full record

ArticleJournal of structural biology2013

Web-based visualisation and analysis of 3D electron-microscopy data from EMDB and PDB.

Ingvar Lagerstedt, William J Moore, Ardan Patwardhan, Eduardo Sanz-García, Christoph Best, Jason R Swedlow, Gerard J Kleywegt

Abstract read
In one paragraph

Article in Journal of structural biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Recognizing amino acid sidechains in a medium-resolution cryo-electron density map.Protein science : a publication of the Protein Society · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. EMDB-the Electron Microscopy Data Bank.Nucleic acids research · 2024
    Review
  7. Article
  8. Assessment of three-dimensional RNA structure prediction in CASP15.bioRxiv : the preprint server for biology · 2023
    Article
  9. Review
  10. Review
  11. Validation analysis of EMDB entries.Acta crystallographica. Section D, Structural biology · 2022
    Article
  12. Atomic model validation using the CCP-EM software suite.Acta crystallographica. Section D, Structural biology · 2022
    Article
  13. Article
  14. Validation, analysis and annotation of cryo-EM structures.Acta crystallographica. Section D, Structural biology · 2021
    Article
  15. Article
  16. Article
  17. Evolving data standards for cryo-EM structures.Structural dynamics (Melville, N.Y.) · 2020
    Article
  18. Article
  19. Review
  20. Real-space refinement in PHENIX for cryo-EM and crystallography.Acta crystallographica. Section D, Structural biology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ingvar LagerstedtProtein Data Bank in Europe, European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SD, United Kingdom. Electronic address: ingvar@ebi.ac.uk.
William J Moore
Ardan Patwardhan
Eduardo Sanz-García
Christoph Best
Jason R Swedlow
Gerard J Kleywegt

Funding

Unified Data Resource for Large Complexes Determined by Cryo-Electron MicroscopyR01GM079429 · NIGMS · STANFORD UNIVERSITY · PI CHIU, WAH · 2007 to 2021
$11.6M
Biotechnology and Biological Sciences Research Council BB/G022585/1Biotechnology and Biological Sciences Research Council G022577Biotechnology and Biological Sciences Research Council G022585NIGMS NIH HHS 1 R01GM079429-01A1NIGMS NIH HHS 2 R01 GM079429-06A1NIGMS NIH HHS R01 GM079429Wellcome Trust 085982Wellcome Trust 088944Wellcome Trust 095931Wellcome Trust 097945
6 · The paper itself

Abstract

The Protein Data Bank in Europe (PDBe) has developed web-based tools for the visualisation and analysis of 3D electron microscopy (3DEM) structures in the Electron Microscopy Data Bank (EMDB) and Protein Data Bank (PDB). The tools include: (1) a volume viewer for 3D visualisation of maps, tomograms and models, (2) a slice viewer for inspecting 2D slices of tomographic reconstructions, and (3) visual analysis pages to facilitate analysis and validation of maps, tomograms and models. These tools were designed to help non-experts and experts alike to get some insight into the content and assess the quality of 3DEM structures in EMDB and PDB without the need to install specialised software or to download large amounts of data from these archives. The technical challenges encountered in developing these tools, as well as the more general considerations when making archived data available to the user community through a web interface, are discussed.

Indexed as

Databases, ProteinSoftwareElectron Microscope TomographyImaging, Three-DimensionalInternetModels, MolecularProteinsProtein Structure, QuaternaryProteins3DEMElectron microscopyElectron Microscopy Data BankElectron Microscopy Validation Task ForceElectron tomographyEMDBEM VTCFourier Shell CorrelationFSCMacromolecular structureOAVOMEOME Remote ObjectsOMEROOpen Astex ViewerOpen Microscopy EnvironmentPDBPDBeProtein Data BankProtein Data Bank in EuropeThree-Dimensional Electron MicroscopyVisualisationWorldwide Protein Data BankwwPDB

Identifiers

PMID24113529
PMCPMC3898923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.