Evidence map›Paper›PMID 24113297›Full record

ArticleJournal of the mechanical behavior of biomedical materials2014

Effects of different post-spin stretching conditions on the mechanical properties of synthetic spider silk fibers.

Amy E Albertson, Florence Teulé, Warner Weber, Jeffery L Yarger, Randolph V Lewis

Abstract read
In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Spider Silk-Inspired Artificial Fibers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Development of a Process for the Spinning of Synthetic Spider Silk.ACS biomaterials science & engineering · 2015
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amy E AlbertsonDepartment of Molecular Biology, University of Wyoming, Laramie, WY 82071, USA. Electronic address: aalberts@uwyo.edu.
Florence Teulé
Warner Weber
Jeffery L Yarger
Randolph V Lewis

Funding

X-RAY STUDY OF HORMONE-RECEPTOR AND PROTEIN-ANTIBODY COMPLEXESP41RR007707 · NCRR · UNIVERSITY OF CHICAGO · PI YANG, XIANGZHONG · 2002 to 2011
$17.3M
Designing Spider Silk Proteins as Novel BiomaterialsR01EB000490 · NIBIB · UNIVERSITY OF WYOMING · PI LEWIS, RANDOLPH V. · 2003 to 2009
$2.4M
BioCARS: A Synchrotron Structure Biology ResourceR24GM111072 · NIGMS · UNIVERSITY OF CHICAGO · PI MOFFAT, JOHN KEITH · 2013 to 2016
$2.3M
BioCARS: A Synchroton Structural Biology ResourceP41GM103543 · NIGMS · UNIVERSITY OF CHICAGO · PI MOFFAT, JOHN KEITH · 2012 to 2012
$1.1M
NCRR NIH HHS 5P41RR007707NCRR NIH HHS P41 RR007707NIBIB NIH HHS EB000490NIBIB NIH HHS R01 EB000490NIGMS NIH HHS 8P41GM103543NIGMS NIH HHS P41 GM103543NIGMS NIH HHS R24 GM111072
6 · The paper itself

Abstract

Spider silk is a biomaterial with impressive mechanical properties, resulting in various potential applications. Recent research has focused on producing synthetic spider silk fibers with the same mechanical properties as the native fibers. For this study, three proteins based on the Argiope aurantia Major ampullate Spidroin 2 consensus repeat sequence were expressed, purified and spun into fibers. A number of post-spin draw conditions were tested to determine the effect of each condition on the mechanical properties of the fiber. In all cases, post-spin stretching improved the mechanical properties of the fibers. Aqueous isopropanol was the most effective solution for increasing extensibility, while other solutions worked best for each fiber type for increasing tensile strength. The strain values of the stretched fibers correlated with the length of the proline-rich protein sequence. Structural analysis, including X-ray diffraction and Raman spectroscopy, showed surprisingly little change in the initial as-spun fibers compared with the post-spin stretched fibers.

Indexed as

Mechanical Phenomena2-PropanolAmino Acid SequenceAnimalsBiomimetic MaterialsElectrophoresisEthanolMaterials TestingMolecular Sequence DataSilkSpidersTemperature2-PropanolEthanolSilkArgiope aurantiaDraglineMechanical propertiesPost-spinningSynthetic spider silk fibers

Identifiers

PMID24113297
PMCPMC4068612

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.