ArticleDental materials : official publication of the Academy of Dental Materials2014
Present and future of glass-ionomers and calcium-silicate cements as bioactive materials in dentistry: biophotonics-based interfacial analyses in health and disease.
Article in Dental materials : official publication of the Academy of Dental Materials, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
58 citing papers in PubMed, 133 citations in OpenAlex.
- Clinical and Radiographic Evaluation of Biodentine and Mineral Trioxide Aggregate as Indirect Pulp Capping Agents in Primary Molars: A Randomized Controlled Trial with 18-month Follow-up.Annals of African medicine · 2025Trial
- Evaluation of the efficacy of calcium silicate vs. glass ionomer cement indirect pulp capping and restoration assessment criteria: a randomised controlled clinical trial-2-year results.Clinical oral investigations · 2019Trial
- Clinical and radiographic assessment of the efficacy of calcium silicate indirect pulp capping: a randomized controlled clinical trial.Journal of dental research · 2015Trial
- Calcium silicate cement with phosphate-based glass for enhanced osteogenic activity and mechanical strength.Clinical oral investigations · 2026Article
- Ultrasonic activation improves bond strength of calcium silicate-based sealers to dentin: an in vitro study.BMC oral health · 2026Article
- Effect of dentine moisture conditions on interfacial adaptation of a calcium silicate-based sealer compared with an epoxy resin-based sealer: an SEM/EDX analysis.Biomaterial investigations in dentistry · 2026Article
- Sealing Ability of Polydopamine-Coated Gutta-Percha With Bioceramic Sealer: An In Vitro Study.International journal of dentistry · 2026Article
- Comparative analysis of fluoride release from type II GIC, ketac molar and ketac universal: AnBioinformation · 2026Article
- Fracture Resistance of Roots With Si̇mulated Internal Root Resorption Followi̇ng Repair With Calcium Silicate-Based Cements.International journal of dentistry · 2026Article
- Urethane Tetramethacrylate Monomers and Nano-Fillers Enhance Dentin Bond Strength of a One-Step Universal Adhesive.The journal of adhesive dentistry · 2025Article
- Osteogenic Potential of Various Premixed Hydraulic Calcium Silicate-Based Sealers on Human Bone Marrow Stem Cells.Materials (Basel, Switzerland) · 2025Article
- Comparison of remineralization in caries-affected dentin using calcium silicate, glass ionomer cement, and resin-modified glass ionomer cement: an in vitro study.Restorative dentistry & endodontics · 2025Article
- Bond Strength of an Epoxy Resin Root Canal Sealer Prototype.Dentistry journal · 2025Article
- In Vitro Bioactivity and Cytotoxicity Assessment of Two Root Canal Sealers.Materials (Basel, Switzerland) · 2025Article
- Evaluating the penetration, interfacial adaptation, and push-out bond strength of four bioceramic-based root canal sealers.BMC oral health · 2025Article
- Comparative evaluation of sealing potential of mineral trioxide aggregate, biodentine, and bio-C repair in furcation perforations: A glucose penetration study.Journal of conservative dentistry and endodontics · 2025Article
- Apical Microleakage of Endoseal MTA, AH26, and Sure-Seal Root Canal Sealers Using a Bacterial Leakage Model: An In-Vitro Study.Frontiers in dentistry · 2025Article
- Immediate and delayed shear bond strength evaluation between root canal sealers and restorative materials: an experimental study.BMC oral health · 2024Article
- Comparison of remineralization ability of tricalcium silicate and of glass ionomer cement on residual dentin: an in vitro study.BMC oral health · 2024Article
- Comparison of the stress distribution in base materials and thicknesses in composite resin restorations.Heliyon · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveSince their introduction, calcium silicate cements have primarily found use as endodontic sealers, due to long setting times. While similar in chemistry, recent variations such as constituent proportions, purities and manufacturing processes mandate a critical understanding of service behavior differences of the new coronal restorative material variants. Of particular relevance to minimally invasive philosophies is the potential for ion supply, from initial hydration to mature set in dental cements. They may be capable of supporting repair and remineralization of dentin left after decay and cavity preparation, following the concepts of ion exchange from glass ionomers.
methodsThis paper reviews the underlying chemistry and interactions of glass ionomer and calcium silicate cements, with dental tissues, concentrating on dentin-restoration interface reactions. We additionally demonstrate a new optical technique, based around high resolution deep tissue, two-photon fluorescence and lifetime imaging, which allows monitoring of undisturbed cement-dentin interface samples behavior over time.
resultsThe local bioactivity of the calcium-silicate based materials has been shown to produce mineralization within the subjacent dentin substrate, extending deep within the tissues. This suggests that the local ion-rich alkaline environment may be more favorable to mineral repair and re-construction, compared with the acidic environs of comparable glass ionomer based materials. SIGNIFICANCE: The advantages of this potential re-mineralization phenomenon for minimally invasive management of carious dentin are self-evident. There is a clear need to improve the bioactivity of restorative dental materials and these calcium silicate cement systems offer exciting possibilities in realizing this goal.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.