ArticleScientific reports2013
A genome-wide analysis of annexins from parasitic organisms and their vectors.
Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 58 citations in OpenAlex.
- Characterization of antigenic proteins of the Taenia solium postoncospheral form.Molecular and biochemical parasitology · 2024Article
- Subtelomeric plasticity contributes to gene family expansion in the human parasitic flatworm Schistosoma mansoni.BMC genomics · 2024Article
- Annexin gene family in Spirometra mansoni (Cestoda: Diphyllobothriidae) and its phylogenetic pattern among Platyhelminthes of medical interest.Parasite (Paris, France) · 2024Article
- Molecular and functional characterization of Schistosoma japonicum annexin A13.Veterinary research · 2023Article
- Review
- Proteomic and Immunological Identification of Diagnostic Antigens from Spirometra erinaceieuropaei Plerocercoid.The Korean journal of parasitology · 2021Article
- Transcriptomic Analysis of the Early Strobilar Development ofPathogens (Basel, Switzerland) · 2020Article
- High-quality Schistosoma haematobium genome achieved by single-molecule and long-range sequencing.GigaScience · 2019Article
- The enigmatic role of fungal annexins: the case of Cryptococcus neoformans.Microbiology (Reading, England) · 2019Article
- Article
- Annexins as Overlooked Regulators of Membrane Trafficking in Plant Cells.International journal of molecular sciences · 2017Review
- Characterization of a Secretory Annexin in Echinococcus granulosus.The American journal of tropical medicine and hygiene · 2016Article
- Structure-function analysis of apical membrane-associated molecules of the tegument of schistosome parasites of humans: prospects for identification of novel targets for parasite control.British journal of pharmacology · 2015Review
- An integrated Java tool for generating amino acid sequence alignments with mapped secondary structure elements.3 Biotech · 2015Article
- Fungal annexins: a mini review.SpringerPlus · 2015Review
- Bioinformatics analysis of bacterial annexins--putative ancestral relatives of eukaryotic annexins.PloS one · 2014Article
- Article
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Authors and funding
12 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, we conduct an in-depth analysis of annexin proteins from a diverse range of invertebrate taxa, including the major groups that contain the parasites and vector organisms that are harmful to humans and domestic animals. Using structure-based amino acid sequence alignments and phylogenetic analyses, we present a classification for this protein group and assign names to sequences with ambiguous annotations in public databases. Our analyses reveal six distinct annexin clades, and the mapping of genes encoding annexins to the genome of the human blood fluke Schistosoma mansoni supports the hypothesis of gene duplication as a major evolutionary event in annexin genesis. This study illuminates annexin diversity from a novel perspective using contemporary phylogenetic hypotheses of eukaryote evolution, and will aid the consolidation of annexin protein identities in public databases and provide a foundation for future functional analysis and characterisation of these proteins in parasites of socioeconomic importance.
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