Evidence map›Paper›PMID 24112988›Full record

ReviewCurrent biology : CB2013

Dynamin assembly strategies and adaptor proteins in mitochondrial fission.

Huyen T Bui, Janet M Shaw

Abstract readReview
In one paragraph

Review in Current biology : CB, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed.

  1. Article
  2. The trypanosomatid dynamin-like protein associates with glycosomes.bioRxiv : the preprint server for biology · 2026
    Article
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Huyen T BuiDepartment of Biochemistry, University of Utah School of Medicine, Salt Lake City, UT 84112, USA.
Janet M Shaw

Funding

REGULATION OF MITOCHONDRIAL INHERITANCE IN YEASTR01GM053466 · NIGMS · UNIVERSITY OF UTAH · PI SHAW, JANET M. · 1996 to 2013
$4.6M
Mechanisms of Mitochondrial DistributionR01GM084970 · NIGMS · UNIVERSITY OF UTAH · PI SHAW, JANET M. · 2008 to 2017
$2.8M
NIGMS NIH HHS GM53466NIGMS NIH HHS GM84970NIGMS NIH HHS R01 GM053466NIGMS NIH HHS R01 GM084970
6 · The paper itself

Abstract

Mitochondrial fission is mediated by a dynamin-related GTPase that assembles at constricted sites on the organelle. The mechanism of action of this GTPase in fission is related to that of classical dynamin, which severs the necks of clathrin-coated pits at the plasma membrane. The scale of these membrane remodeling events differs by an order of magnitude, however, and structural studies have revealed variations in the assembly properties of classical and mitochondrial dynamins that accommodate these differences. Despite this progress, structural and mechanistic models have not yet incorporated a growing number of adaptor proteins that are required for the membrane recruitment and function of mitochondrial dynamins. Here, we review the structure and assembly properties of the yeast and mammalian mitochondrial dynamins and discuss what is known about the activities of their adaptor proteins.

Indexed as

Mitochondrial DynamicsAdaptor Proteins, Signal TransducingAnimalsClathrinCoated Pits, Cell-MembraneDynaminsGuanosine TriphosphateMitochondriaMitochondrial MembranesMitochondrial ProteinsSaccharomyces cerevisiaeAdaptor Proteins, Signal TransducingClathrinDynaminsGuanosine TriphosphateMitochondrial Proteins

Identifiers

PMID24112988
PMCPMC3832257

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.