Evidence map›Paper›PMID 24112429›Full record

ArticlePediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2013

Exposures to molds in school classrooms of children with asthma.

Sachin N Baxi, Michael L Muilenberg, Christine A Rogers, William J Sheehan, Jonathan Gaffin, Perdita Permaul, Lianne S Kopel, Peggy S Lai, Jeffrey P Lane, Ann Bailey and 4 more

Abstract read
In one paragraph

Article in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Medicina (Kaunas, Lithuania) · 2025
    Review
  2. Review
  3. Article
  4. Environmental Exposures Impact Pediatric Asthma Within the School Environment.Immunology and allergy clinics of North America · 2022
    Review
  5. Household mold, pesticide use, and childhood asthma: A nationwide study in the U.S.International journal of hygiene and environmental health · 2021
    Article
  6. The Indoor Environment and Childhood Asthma.Current allergy and asthma reports · 2020
    Review
  7. Asthma and Allergies in the School Environment.Clinical reviews in allergy & immunology · 2019
    Review
  8. Association between fungal spore exposure in inner-city schools and asthma morbidity.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2019
    Article
  9. The Effects of the Environment on Asthma Disease Activity.Immunology and allergy clinics of North America · 2019
    Review
  10. Inner-City Asthma in Children.Clinical reviews in allergy & immunology · 2019
    Review
  11. School exposure and asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2018
    Review
  12. A Practical Approach to Severe Asthma in Children.Annals of the American Thoracic Society · 2018
    Review
  13. Article
  14. Article
  15. Subchronic exposures to fungal bioaerosols promotes allergic pulmonary inflammation in naïve mice.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2016
    Article
  16. Recent advances in environmental controls outside the home setting.Current opinion in allergy and clinical immunology · 2016
    Review
  17. Inner city asthma.Immunology and allergy clinics of North America · 2015
    Review
  18. Mold contamination in schools with either high or low prevelance of asthma.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2015
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sachin N BaxiDivision of Allergy and Immunology, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Michael L Muilenberg
Christine A Rogers
William J Sheehan
Jonathan Gaffin
Perdita Permaul
Lianne S Kopel
Peggy S Lai
Jeffrey P Lane
Ann Bailey
Carter R Petty
Chunxia Fu
Diane R Gold
Wanda Phipatanakul

Funding

HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
AsthmaNet: Brigham and Women's Hospital & Children's Hospital BostonU10HL098102 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, PHIPATANAKUL, WANDA · 2009 to 2015
$5.5M
ALLERGENS IN INNER-CITY SCHOOLS AND CHILDHOOD ASTHMAR01AI073964 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2008 to 2012
$4.6M
Midcareer Investigator Award: Urban School Allergen Exposures and Childhood AsthmK24AI106822 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2013 to 2022
$1.9M
School-based air pollution and asthma morbidity in Inner City School ChildrenK23AI106945 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI GAFFIN, JONATHAN MARK · 2013 to 2017
$822k
Endotoxin, the airway transcriptome, and obstructive lung diseaseK23ES023700 · NIEHS · MASSACHUSETTS GENERAL HOSPITAL · PI LAI, PEGGY SUE · 2013 to 2017
$764k
NCRR NIH HHS UL1 RR 025758NCRR NIH HHS UL1 RR025758NHLBI NIH HHS U10 HL098102NHLBI NIH HHS U10HL098102NIAID NIH HHS K23 AI106945NIAID NIH HHS K24 AI 106822NIAID NIH HHS K24 AI106822NIAID NIH HHS R01 AI 073964NIAID NIH HHS R01 AI073964NIAID NIH HHS R01 AI 073964-02S1NIEHS NIH HHS K23 ES023700
6 · The paper itself

Abstract

backgroundStudents spend a large portion of their day in classrooms which may be a source of mold exposure. We examined the diversity and concentrations of molds in inner-city schools and described differences between classrooms within the same school.

methodsClassroom airborne mold spores, collected over a 2 day period, were measured twice during the school year by direct microscopy.

resultsThere were 180 classroom air samples collected from 12 schools. Mold was present in 100% of classrooms. Classrooms within the same school had differing mold levels and mold diversity scores. The total mold per classroom was 176.6 ± 4.2 spores/m3 (geometric mean ± standard deviation) and ranged from 11.2 to 16,288.5 spores/m3. Mold diversity scores for classroom samples ranged from 1 to 19 (7.7 ± 3.5). The classroom accounted for the majority of variance (62%) in the total mold count, and for the majority of variance (56%) in the mold diversity score versus the school. The species with the highest concentrations and found most commonly included Cladosporium (29.3 ± 4.2 spores/m3), Penicillium/Aspergillus (15.0 ± 5.4 spores/m3), smut spores (12.6 ± 4.0 spores/m3), and basidiospores (6.6 ± 7.1 spores/m3).

conclusionsOur study found that the school is a source of mold exposure, but particularly the classroom microenvironment varies in quantity of spores and species among classrooms within the same school. We also verified that visible mold may be a predictor for higher mold spore counts. Further studies are needed to determine the clinical significance of mold exposure relative to asthma morbidity in sensitized and non-sensitized asthmatic children.

Indexed as

Air Pollution, IndoorAllergensChildColony Count, MicrobialFungiHumansSchoolsSeasonsSpores, FungalUrban PopulationAllergensasthmachildrenfungusinner-citymoldschool

Identifiers

PMID24112429
PMCPMC3782748

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.