Evidence map›Paper›PMID 24112239›Full record

ArticleThe American journal on addictions

The lifetime prevalence of anabolic-androgenic steroid use and dependence in Americans: current best estimates.

Harrison G Pope, Gen Kanayama, Alison Athey, Erin Ryan, James I Hudson, Aaron Baggish

Abstract read
In one paragraph

Article in The American journal on addictions. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed, 3 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 3 syntheses or guidelines pooled it, 307 citations in OpenAlex.

  1. Pooled it
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  6. Health consequences of anabolic steroids: a sexual-medicine perspective.International journal of impotence research · 2026
    Review
  7. Muscle dysmorphia in adolescents and young adults.The Lancet. Child & adolescent health · 2026
    Review
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45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Harrison G PopeBiological Psychiatry Laboratory, McLean Hospital, Belmont, Massachusetts; Department of Psychiatry, Harvard Medical School, Boston, Massachusetts.
Gen Kanayama
Alison Athey
Erin Ryan
James I Hudson
Aaron Baggish
Harvard University · USMcLean Hospital · US

Funding

Medical Consequences of Long-Term Anabolic-Androgenic Steroid AbuseR01DA029141 · NIDA · MCLEAN HOSPITAL · PI POPE, HARRISON G · 2011 to 2015
$2.5M
NIDA NIH HHS DA‐029141NIDA NIH HHS R01 DA029141
6 · The paper itself

Abstract

BACKGROUND AND

objectivesAlthough various surveys have tracked the prevalence of anabolic-androgenic steroid (AAS) use in American teenagers and young adults, no recent surveys have assessed the lifetime prevalence of AAS use in Americans overall. We therefore analyzed serial youth-survey data to derive estimates of the lifetime prevalence of AAS use in the current American general population.

methodsWe first determined the distribution of age of onset of AAS use, based on pooled data from nine studies. Using this distribution, we then developed equations to project the eventual lifetime prevalence of AAS use among young survey respondents, once they aged and completed the period of risk for initiating AAS. We similarly calculated the denominator of lifetimes of risk for AAS use in the total American population. We next applied these equations to four independent national youth datasets to derive current American general-population estimates for lifetime AAS use. Finally, using data from 10 pooled studies, we estimated the lifetime prevalence of AAS dependence among AAS users.

resultsAge-of-onset studies consistently showed that AAS use begins later than most drugs, with only 22% of users (95% confidence interval: 19-25%) starting before age 20. Applying the age-of-onset findings to national youth datasets, we estimated that among Americans currently age 13-50 years, 2.9-4.0 million have used AAS. Within this group, roughly 1 million may have experienced AAS dependence. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Although subject to various limitations, our estimation techniques suggest a surprisinigly high prevalence of AAS use and dependence among Americans.

Indexed as

Models, StatisticalAdolescentAdultAge of OnsetAnabolic AgentsAndrogensFemaleHealth SurveysHumansMaleMiddle AgedPrevalenceSubstance-Related DisordersUnited StatesYoung AdultAnabolic AgentsAndrogens

Identifiers

PMID24112239
PMCPMC3961570
OpenAlexW1512463247

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.