ArticleBMC infectious diseases2013
The potential impact of routine testing of individuals with HIV indicator diseases in order to prevent late HIV diagnosis.
Article in BMC infectious diseases, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.
- Low levels of HIV test coverage in clinical settings in the U.K.: a systematic review of adherence to 2008 guidelines.Sexually transmitted infections · 2014Pooled it
- Evaluation of an educational intervention to increase HIV-testing in high HIV prevalence general practices: a pilot feasibility stepped-wedged randomised controlled trial.BMC family practice · 2018Trial
- Implicit bias in HIV testing based on indicator conditions in primary care: a population-based study in Catalonia, Spain, 2017 to 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025Article
- Use of healthcare services preceding HIV diagnosis - missed opportunities for earlier diagnosis, Finland, 1996 to 2019.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025Article
- Late presentations and missed opportunities among newly diagnosed HIV patients presenting to a specialty clinic in Lebanon.Scientific reports · 2024Article
- Mapping hematologists' HIV testing behavior among lymphoma patients-A mixed-methods study.PloS one · 2023Article
- Review
- Determinants of Late HIV Presentation at Ndlavela Health Center in Mozambique.International journal of environmental research and public health · 2022Article
- Features of the Skin Microbiota in Common Inflammatory Skin Diseases.Life (Basel, Switzerland) · 2021Review
- Promoting HIV indicator condition-guided testing in hospital settings (PROTEST 2.0): study protocol for a multicentre interventional study.BMC infectious diseases · 2021Article
- Current evidence on the adoption of indicator condition guided testing for HIV in western countries: A systematic review and meta-analysis.EClinicalMedicine · 2021Article
- Algorithmic prediction of HIV status using nation-wide electronic registry data.EClinicalMedicine · 2019Article
- Trends in HIV testing in the UK primary care setting: a 15-year retrospective cohort study from 2000 to 2015.BMJ open · 2019Article
- Qualitative evaluation of a pilot educational intervention to increase primary care HIV-testing.BMC family practice · 2019Article
- Missed opportunities for earlier diagnosis of HIV in British Columbia, Canada: A retrospective cohort study.PloS one · 2019Article
- Late Presentation of HIV Infection in the Netherlands: Reasons for Late Diagnoses and Impact on Vocational Functioning.AIDS and behavior · 2018Article
- "Late for testing, early for antiretroviral therapy, less likely to die": results from a large HIV cohort study in China, 2006-2014.BMC infectious diseases · 2018Article
- Pregnant with HIV before age 25: data from a large national study in Italy, 2001-2016.Epidemiology and infection · 2017Article
- Missed opportunities for earlier diagnosis of HIV in patients who presented with advanced HIV disease: a retrospective cohort study.BMJ open · 2016Observational
- Article
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Authors and funding
15 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of our work was to evaluate the potential impact of the European policy of testing for HIV all individuals presenting with an indicator disease, to prevent late diagnosis of HIV. We report on a retrospective analysis among individuals diagnosed with HIV to assess whether a history of certain diseases prior to HIV diagnosis was associated with the chance of presenting late for care, and to estimate the proportion of individuals presenting late who could have been diagnosed earlier if tested when the indicator disease was diagnosed.
methodsWe studied a large cohort of individuals newly diagnosed with HIV infection in 13 counselling and testing sites in the Lazio Region, Italy (01/01/2004-30/04/2009). Considered indicator diseases were: viral hepatitis infection (HBV/HCV), sexually transmitted infections, seborrhoeic dermatitis and tuberculosis. Logistic regression analysis was performed to estimate association of occurrence of at least one indicator disease with late HIV diagnosis.
resultsIn our analysis, the prevalence of late HIV diagnosis was 51.3% (890/1735). Individuals reporting at least one indicator disease before HIV diagnosis (29% of the study population) had a lower risk of late diagnosis (OR = 0.7; 95%CI: 0.5-0.8) compared to those who did not report a previous indicator disease. 52/890 (5.8%) late presenters were probably already infected at the time the indicator disease was diagnosed, a median of 22.6 months before HIV diagnosis.
conclusionsOur data suggest that testing for HIV following diagnosis of an indicator disease significantly decreases the probability of late HIV diagnosis. Moreover, for 5.5% of late HIV presenters, diagnosis could have been anticipated if they had been tested when an HIV indicator disease was diagnosed.However, this strategy for enhancing early HIV diagnosis needs to be complemented by client-centred interventions that aim to increase awareness in people who do not perceive themselves as being at risk for HIV.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.