ReviewAnnual review of medicine2014
Male circumcision: a globally relevant but under-utilized method for the prevention of HIV and other sexually transmitted infections.
Review in Annual review of medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Critical evaluation of arguments opposing male circumcision: A systematic review.Journal of evidence-based medicine · 2019Pooled it
- HIV shedding from male circumcision wounds in HIV-infected men: a prospective cohort study.PLoS medicine · 2015Trial
- Association between male circumcision and incidence of syphilis in men and women: a prospective study in HIV-1 serodiscordant heterosexual African couples.The Lancet. Global health · 2014Trial
- Novel penile circumcision suturing devices versus the shang ring for adult male circumcision: a prospective study.International braz j urol : official journal of the Brazilian Society of UrologyTrial
- Understanding stakeholder perspectives on integrating and sustaining a vertical HIV prevention programme into routine health services in Zimbabwe: a qualitative study.BMJ global health · 2025Article
- Factors influencing neonatal male circumcision uptake among expecting couples in Zambia: formative findings.AIDS care · 2024Article
- Sustainable surgical resource initiative for Haiti: the SSRI-Haiti project.Global health action · 2023Article
- Comments by opponents on the British Medical Association's guidance on non-therapeutic male circumcision of children seem one-sided and may undermine public health.World journal of clinical pediatrics · 2023Article
- HIV infection.Nature reviews. Disease primers · 2023Review
- Cost-effectiveness of voluntary medical male circumcision for HIV prevention across sub-Saharan Africa: results from five independent models.The Lancet. Global health · 2023Article
- Estimating the effect of HIV on cervical cancer elimination in South Africa: Comparative modelling of the impact of vaccination and screening.EClinicalMedicine · 2022Article
- Infant Circumcision for Sexually Transmitted Infection Risk Reduction Globally.Global health, science and practice · 2022Article
- Evidence-based circumcision policy for Australia.Journal of men's health · 2022Article
- Insertive condom-protected and condomless vaginal sex both have a profound impact on the penile immune correlates of HIV susceptibility.PLoS pathogens · 2022Article
- Association of medical male circumcision and sexually transmitted infections in a population-based study using targeted maximum likelihood estimation.BMC public health · 2021Article
- Mobile Device Usage by Gender Among High-Risk HIV Individuals in a Rural, Resource-Limited Setting.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2021Article
- Article
- Sexual function after voluntary medical male circumcision for human immunodeficiency virus prevention: Results from a programmatic delivery setting in Botswana.Southern African journal of HIV medicine · 2020Article
- The past, present and future impact of HIV prevention and control on HPV and cervical disease in Tanzania: A modelling study.PloS one · 2020Article
- When Religion and Medicine Clash: Non-beneficial Treatments and Hope for a Miracle.HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Randomized trials have demonstrated that male circumcision (MC) reduces heterosexual acquisition of HIV, herpes simplex virus type 2, human papillomavirus (HPV), and genital ulcer disease among men, and it reduces HPV, genital ulcer disease, bacterial vaginosis, and trichomoniasis among female partners. The pathophysiology behind these effects is multifactorial, relying on anatomic and cellular changes. MC is cost effective and potentially cost saving in both the United States and Africa. The World Health Organization and Joint United Nations Program on HIV/AIDS proposed reaching 80% MC coverage in HIV endemic countries, but current rates fall far behind targets. Barriers to scale-up include supply-side and demand-side challenges. In the United States, neonatal MC rates are decreasing, but the American Academy of Pediatrics now recognizes the medical benefits of MC and supports insurance coverage. Although MC is a globally valuable tool to prevent HIV and other sexually transmitted infections, it is underutilized. Further research is needed to address barriers to MC uptake.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.