Evidence map›Paper›PMID 24109639›Full record

ReviewAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference2013

New methods for quantifying and visualizing information from images of cells: An overview.

Gustavo Kunde Rohde

Abstract readReview
In one paragraph

Review in Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. In Situ Classification of Cell Types in Human Kidney Tissue Using 3D Nuclear Staining.Cytometry. Part A : the journal of the International Society for Analytical Cytology · 2021
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Gustavo Kunde Rohde

Funding

Image-derived Spatiotemporal Models of Cellular Organization and PerturbationR01GM090033 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI MURPHY, ROBERT F, ROHDE, GUSTAVO KUNDE · 2010 to 2018
$2.4M
Deformation-Based Computational Morphometry for Cell Biology ApplicationsR21GM088816 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI ROHDE, GUSTAVO KUNDE · 2009 to 2010
$333k
NIGMS NIH HHS GM088816NIGMS NIH HHS GM090033NIGMS NIH HHS R01 GM090033NIGMS NIH HHS R21 GM088816
6 · The paper itself

Abstract

New microscopy imaging techniques have enabled the acquisition of cellular and sub-cellular information with unprecedented accuracy and specificity. Fluorescence techniques have enabled labeling of numerous, previously inaccessible, molecules and organelles, while Raman spectrographic techniques, for example, have enabled label free acquisition. Together with the development of high throughput techniques, these technologies now allow for the acquisition of a significant amount of information about cellular processes and have enabled high throughput and high content screening. Beyond image formation and acquisition, computational techniques comprise an important part of the process of obtaining biological understanding from such experiments. Here we review the pros and cons of the main approaches that have been used to extract information from digital images of cells. In addition, we also offer an overview of modern computational techniques that beyond allowing for discrimination between two hypothesis, also allow for modeling, visualization, and understanding of biological phenomena.

Indexed as

Microscopy, FluorescenceCell Line, TumorCell NucleusGlioblastomaHumansImaging, Three-DimensionalPharmaceutical PreparationsProteinsRNA InterferenceSpectrum Analysis, RamanPharmaceutical PreparationsProteins

Identifiers

PMID24109639
PMCPMC5884071

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.