ArticleFrontiers in behavioral neuroscience2013
Serotonin enhances solitariness in phase transition of the migratory locust.
Article in Frontiers in behavioral neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review of locust phase polyphenism: from proximate mechanisms to ecology and management.PeerJ · 2026Pooled it
- Rapid behavioural gregarization in the desert locust, Schistocerca gregaria entails synchronous changes in both activity and attraction to conspecifics.Journal of insect physiology · 2014Pooled it
- Behavioural phase transitions in the migratory locust,ISME communications · 2026Article
- Phonotaxis in Male Field Crickets: The Role of Flight Experience, Serotonin and Octopamine Neurotransmission.Insects · 2025Article
- Comparative transcriptomics suggests a highly species-specific nature of the phenotypic plasticity associated with the outbreaks of the two main pest locusts.BMC genomics · 2024Article
- Serotonergic amplification of odor-evoked neural responses maps onto flexible behavioral outcomes.eLife · 2024Article
- Monoaminergic Systems in Flight-Induced Potentiation of Phonotactic Behavior in Female CricketsInsects · 2024Article
- Glutamate-GABA imbalance mediated by miR-8-5p and its STTM regulates phase-related behavior of locusts.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Serotonin/GABA receptors modulate odor input to olfactory receptor neuron in locusts.Frontiers in cellular neuroscience · 2023Article
- The time course of behavioural phase change in the Central American locust Schistocerca piceifrons.The Journal of experimental biology · 2022Article
- Sulfation modification of dopamine in brain regulates aggregative behavior of animals.National science review · 2022Article
- Janus Kinase Mediates Faster Recovery From Sevoflurane Anesthesia Than Isoflurane Anesthesia in the Migratory Locusts.Frontiers in physiology · 2022Article
- Juvenile hormone suppresses aggregation behavior through influencing antennal gene expression in locusts.PLoS genetics · 2020Article
- Phenylethylamides derived from bacterial secondary metabolites specifically inhibit an insect serotonin receptor.Scientific reports · 2019Article
- CREB-B acts as a key mediator of NPF/NO pathway involved in phase-related locomotor plasticity in locusts.PLoS genetics · 2019Article
- Molecular Cloning and Expression Analysis of 5-hydroxytryptamine Receptor 7 in Ant Polyrhachis vicina Roger (Hymenoptera: Formicidae).Journal of insect science (Online) · 2019Article
- RNA-Seq reveals large quantitative differences between the transcriptomes of outbreak and non-outbreak locusts.Scientific reports · 2018Article
- Evolution, expression and association of the chemosensory protein genes with the outbreak phase of the two main pest locusts.Scientific reports · 2017Article
- Phylogeny of locusts and grasshoppers reveals complex evolution of density-dependent phenotypic plasticity.Scientific reports · 2017Article
- Octopamine and tyramine respectively regulate attractive and repulsive behavior in locust phase changes.Scientific reports · 2015Article
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3 authors.
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Abstract
The behavioral plasticity of locusts is a striking trait presented during the reversible phase transition between solitary and gregarious individuals. However, the results of serotonin as a neurotransmitter from the migratory locust Locusta migratoria in phase transition showed an alternative profile compared to the results from the desert locust Schistocerca gregaria. In this study, we investigated the roles of serotonin in the brain during the phase change of the migratory locust. During the isolation of gregarious nymphs, the concentration of serotonin in the brain increased significantly, whereas serotonin receptors (i.e., 5-HT 1 , 5-HT 2 , and 5-HT 7 ) we identified here showed invariable expression patterns. Pharmacological intervention showed that serotonin injection in the brain of gregarious nymphs did not induced the behavioral change toward solitariness, but injection of this chemical in isolated gregarious nymphs accelerated the behavioral change from gregarious to solitary phase. During the crowding of solitary nymphs, the concentration of serotonin in the brain remained unchanged, whereas 5-HT 2 increased after 1 h of crowding and maintained stable expression level thereafter. Activation of serotonin-5-HT2 signaling with a pharmaceutical agonist inhibited the gregariousness of solitary nymphs in crowding treatment. These results indicate that the fluctuations of serotonin content and 5-HT 2 expression are results of locust phase change. Overall, this study demonstrates that serotonin enhances the solitariness of the gregarious locusts. Serotonin may regulate the withdrawal-like behavioral pattern displayed during locust phase change and this mechanism is conserved in different locust species.
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