Evidence map›Paper›PMID 24109228›Full record

ArticleJournal of virology2013

Nonhuman transferrin receptor 1 is an efficient cell entry receptor for Ocozocoautla de Espinosa virus.

Yíngyún Caì, Shuiqìng Yú, Steven Mazur, Lián Dong, Krisztina Janosko, Téngfei Zhang, Marcel A Müller, Lisa E Hensley, Sina Bavari, Peter B Jahrling and 2 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. New World Arenavirus Biology.Annual review of virology · 2017
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Yíngyún CaìIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, Maryland, USA.
Shuiqìng Yú
Steven Mazur
Lián Dong
Krisztina Janosko
Téngfei Zhang
Marcel A Müller
Lisa E Hensley
Sina Bavari
Peter B Jahrling
Sheli R Radoshitzky
Jens H Kuhn
National Institute of Allergy and Infectious Diseases · USNational Institutes of Health · USUnited States Army Medical Research Institute of Infectious Diseases · USUniversity of Bonn · DE

Funding

Integrated Research Facility at Fort DetrickZIDAI009006 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI COE, LINDA · 2009 to 2018
$341.7M
NIAID NIH HHS HHSN272200700016I
6 · The paper itself

Abstract

Ocozocoautla de Espinosa virus (OCEV) is a novel, uncultured arenavirus. We found that the OCEV glycoprotein mediates entry into grivet and bat cells through transferrin receptor 1 (TfR1) binding but that OCEV glycoprotein precursor (GPC)-pseudotyped retroviruses poorly entered 53 human cancer cell lines. Interestingly, OCEV and Tacaribe virus could use bat, but not human, TfR1. Replacing three human TfR1 amino acids with their bat ortholog counterparts transformed human TfR1 into an efficient OCEV and Tacaribe virus receptor.

Indexed as

Virus InternalizationAmino Acid SequenceAnimalsAntigens, CDArenaviridae InfectionsArenaviruses, New WorldCell LineChiropteraChlorocebus aethiopsHumansMolecular Sequence DataReceptors, TransferrinReceptors, VirusSequence AlignmentViral Envelope ProteinsAntigens, CDCD71 antigenReceptors, TransferrinReceptors, VirusViral Envelope Proteins

Identifiers

PMID24109228
PMCPMC3838296
OpenAlexW2134944051

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.