ArticleCerebral cortex (New York, N.Y. : 1991)2015
Refinement but not maintenance of visual receptive fields is independent of visual experience.
Article in Cerebral cortex (New York, N.Y. : 1991), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Chilean brush-tailed mouse (Journal of neurophysiology · 2025Article
- TrkB Activation during a Critical Period Mimics the Protective Effects of Early Visual Experience on Perception and the Stability of Receptive Fields in Adult Superior Colliculus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- The Impact of Ecological Niche on Adaptive Flexibility of Sensory Circuitry.Frontiers in neuroscience · 2017Review
- Reconnecting Eye to Brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Review
- Visual experience prevents dysregulation of GABAB receptor-dependent short-term depression in adult superior colliculus.Journal of neurophysiology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Visual deprivation is reported to prevent or delay the development of mature receptive field (RF) properties in primary visual cortex (V1) in several species. In contrast, visual deprivation neither prevents nor delays refinement of RF size in the superior colliculus (SC) of Syrian hamsters, although vision is required for RF maintenance in the SC. Here, we report that, contrary to expectation, visual cortical RF refinement occurs normally in dark-reared animals. As in the SC, a brief period of visual experience is required to maintain V1 RF refinement in adulthood. Whereas in the SC, 3 days of visual experience within a sensitive period (P37-40) was sufficient to protect RFs from deprivation-induced enlargement in adulthood, 7 days (P33-40) were required for RF size maintenance in V1. Thus, spontaneous activity is sufficient for RF refinement at these 2 levels of the visual pathway, and visual input is necessary only to prevent deprivation-induced RF enlargement in adulthood. These studies show that sensory experience during a late juvenile sensitive period protects the visual pathway against sensory deprivation in adulthood, and suggest that more importance may have been placed on the role of early visual experience in visual RF development than is warranted.
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Registered trials
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