ArticleJournal of neurophysiology2014
An auditory colliculothalamocortical brain slice preparation in mouse.
Article in Journal of neurophysiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Asynchronous development of the mouse auditory cortex is driven by hemispheric identity and sex.Nature communications · 2025Article
- Advances in construction and modeling of functional neural circuits in vitro.Neurochemical research · 2022Article
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- A novel dynamic network imaging analysis method reveals aging-related fragmentation of cortical networks in mouse.Network neuroscience (Cambridge, Mass.) · 2021Article
- A three-dimensional thalamocortical dataset for characterizing brain heterogeneity.Scientific data · 2020Article
- Thalamocortical and Intracortical Inputs Differentiate Layer-Specific Mouse Auditory Corticocollicular Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Dedicated Setup for the Photoconversion of Fluorescent Dyes for Functional Electron Microscopy.Frontiers in cellular neuroscience · 2019Article
- A novel mutual information estimator to measure spike train correlations in a model thalamocortical network.Journal of neurophysiology · 2018Article
- Effect of temperature on FAD and NADH-derived signals and neurometabolic coupling in the mouse auditory and motor cortex.Pflugers Archiv : European journal of physiology · 2017Article
- Presynaptic Neuronal Nicotinic Receptors Differentially Shape Select Inputs to Auditory Thalamus and Are Negatively Impacted by Aging.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Auditory thalamic circuits and GABAHearing research · 2017Review
- Anatomical characterization of subcortical descending projections to the inferior colliculus in mouse.The Journal of comparative neurology · 2017Article
- The impact of aging, hearing loss, and body weight on mouse hippocampal redox state, measured in brain slices using fluorescence imaging.Neurobiology of aging · 2016Article
- Ageing-related changes in GABAergic inhibition in mouse auditory cortex, measured using in vitro flavoprotein autofluorescence imaging.The Journal of physiology · 2016Article
- Open-loop organization of thalamic reticular nucleus and dorsal thalamus: a computational model.Journal of neurophysiology · 2015Article
- Commissural functional topography of the inferior colliculus assessed in vitro.Hearing research · 2015Article
- Modification of a Colliculo-thalamocortical Mouse Brain Slice, Incorporating 3-D printing of Chamber Components and Multi-scale Optical Imaging.Journal of visualized experiments : JoVE · 2015Article
- Stretch induced hyperexcitability of mice callosal pathway.Frontiers in cellular neuroscience · 2015Article
- The auditory corticocollicular system: molecular and circuit-level considerations.Hearing research · 2014Review
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Key questions about the thalamus are still unanswered in part because of the inability to stimulate its inputs while monitoring cortical output. To address this, we employed flavoprotein autofluorescence optical imaging to expedite the process of developing a brain slice in mouse with connectivity among the auditory midbrain, thalamus, thalamic reticular nucleus, and cortex. Optical, electrophysiological, anatomic, and pharmacological tools revealed ascending connectivity from midbrain to thalamus and thalamus to cortex as well as descending connectivity from cortex to thalamus and midbrain and from thalamus to midbrain. The slices were relatively thick (600-700 μm), but, based on typical measures of cell health (resting membrane potential, spike height, and input resistance) and use of 2,3,5-triphenyltetrazolium chloride staining, the slices were as viable as thinner slices. As expected, after electrical stimulation of the midbrain, the latency of synaptic responses gradually increased from thalamus to cortex, and spiking responses were seen in thalamic neurons. Therefore, for the first time, it will be possible to manipulate and record simultaneously the activity of most of the key brain structures that are synaptically connected to the thalamus. The details for the construction of such slices are described herein.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.