Evidence map›Paper›PMID 24108781›Full record

ArticleThe American journal of clinical nutrition2013

Dietary patterns and breast cancer risk in the California Teachers Study cohort.

Lilli B Link, Alison J Canchola, Leslie Bernstein, Christina A Clarke, Daniel O Stram, Giske Ursin, Pamela L Horn-Ross

Open access · bronzeAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of clinical nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 5 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 5 syntheses or guidelines pooled it, 116 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lilli B LinkFrom Cancer Epidemiology, Mailman School of Public Health, Columbia University, New York, NY (LBL); the Cancer Prevention Institute of California, Fremont, CA (AJC, CAC, and PLH-R); the Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA (CAC and PLH-R); the Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA (LB); the Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA (DOS and GU); the Cancer Registry of Norway, Oslo, Norway (GU); and the Department of Nutrition, University of Oslo, Oslo, Norway (GU).
Alison J Canchola
Leslie Bernstein
Christina A Clarke
Daniel O Stram
Giske Ursin
Pamela L Horn-Ross
Cancer Prevention Institute of California · US

Funding

CALIFORNIA TEACHERS STUDYR01CA077398 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BERNSTEIN, LESLIE · 1998 to 2014
$29.7M
Training Program in Cancer-Related Population SciencesR25CA094061 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NEUGUT, ALFRED I. · 2002 to 2016
$5.9M
NCI NIH HHS N01-PC-35136NCI NIH HHS N01-PC-35139NCI NIH HHS R01 CA077398NCI NIH HHS R01 CA77398NCI NIH HHS R25 CA094061PHS HHS U55/CCR921930-02
6 · The paper itself

Abstract

backgroundEvidence that diet is associated with breast cancer risk is inconsistent. Most studies have examined risks associated with specific foods and nutrients, rather than measures of overall diet.

objectiveThis study aimed to evaluate dietary patterns and their relation to breast cancer risk in a large cohort of women.

designData from 91,779 women in the California Teachers Study cohort were analyzed, including data from 4140 women with a diagnosis of invasive breast cancer made between 1995 and 2009. Five predominant dietary patterns were identified by using principal components factor analysis: a plant-based diet, high in fruit and vegetables; a high-protein, high-fat diet, high in meats, eggs, fried foods, and high-fat condiments; a high-carbohydrate diet, high in convenience foods, pasta, and bread products; an ethnic diet, high in legumes, soy-based foods, rice, and dark-green leafy vegetables; and a salad and wine diet, high in lettuce, fish, wine, low-fat salad dressing, and coffee and tea.

resultsThe plant-based pattern was associated with a reduction in breast cancer risk (RR: 0.85; 95% CI: 0.76, 0.95 for the highest compared with the lowest consumption quintile; P-trend = 0.003); risk reduction was greater for estrogen receptor-negative progesterone receptor-negative (ER-PR-) tumors (RR: 0.66; 95% CI: 0.48, 0.91; P-trend = 0.03). The salad and wine pattern was associated with an increased risk of estrogen receptor-positive progesterone receptor-positive tumors (RR: 1.29; 95% CI: 1.12, 1.49); this effect was only slightly attenuated after adjustment for alcohol consumption.

conclusionThe finding that greater consumption of a plant-based dietary pattern is associated with a reduced breast cancer risk, particularly for ER-PR- tumors, offers a potential avenue for prevention.

Indexed as

DietEdible GrainFruitVegetablesAdultBreast NeoplasmsCaliforniaCohort StudiesDiet, VegetarianFacultyFemaleHumansIncidenceMiddle AgedNeoplasm ProteinsPrincipal Component AnalysisNeoplasm ProteinsReceptors, EstrogenReceptors, Progesterone

Identifiers

PMID24108781
PMCPMC3831538
OpenAlexW2154991249

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.