ArticleJournal of medical virology2014
Burden of respiratory viruses in patients with acute respiratory failure.
Article in Journal of medical virology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Society of Critical Care Medicine and the Infectious Diseases Society of America Guidelines for Evaluating New Fever in Adult Patients in the ICU.Critical care medicine · 2023Pooled it
- The frequency of influenza and bacterial coinfection: a systematic review and meta-analysis.Influenza and other respiratory viruses · 2016Pooled it
- Severe viral infections requiring intensive care unit admissions- aetiology, co-infections, respiratory interventions and outcomes.Infection · 2026Article
- Review
- Comparison of critically ill COVID-19 and influenza patients with acute respiratory failure.Acute and critical care · 2022Article
- Respiratory viral infections in pragmatically selected adults in intensive care units.Scientific reports · 2021Article
- Update in Viral Infections in the Intensive Care Unit.Frontiers in medicine · 2021Review
- Incidence and seasonality of respiratory viruses causing acute respiratory infections in the Northern United Arab Emirates.Journal of medical virology · 2019Article
- Impact of microbial Aetiology on mortality in severe community-acquired pneumonia.BMC infectious diseases · 2018Article
- Article
- Clinical practice of respiratory virus diagnostics in critically ill patients with a suspected pneumonia: A prospective observational study.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2016Observational
- Epidemiology, Co-Infections, and Outcomes of Viral Pneumonia in Adults: An Observational Cohort Study.Medicine · 2015Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Respiratory viruses (RVs) are ubiquitous pathogens that represent a major cause of community-acquired pneumonia and chronic pulmonary diseases exacerbations. However, their contribution to acute respiratory failure events requiring intensive care unit admission in the era of rapid multiplex molecular assay deserves further evaluation. This study investigated the burden of viral infections in non immunocompromised patients admitted to the intensive care unit for acute respiratory failure using a multiplex molecular assay. Patients were investigated for RVs using immunofluoresence testing and a commercial multiplex molecular assay, and for bacteria using conventional culture. Half the patients (34/70, 49%) had a documented RVs infection. No other pathogen was found in 24 (71%) patients. Viral infection was detected more frequently in patients with obstructive respiratory diseases (64% vs. 29%; P = 0.0075). Multiplex molecular assay should be considered as an usefull diagnostic tool in patients admitted to the intensive care unit with acute respiratory failure, especially those with acute exacerbations of chronic obstructive pulmonary disease and asthma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.