Evidence map›Paper›PMID 24108584›Full record

ArticleJournal of biomedical materials research. Part A2014

Mechanical and biological properties of chitosan/carbon nanotube nanocomposite films.

Ashkan Aryaei, Ahalapitiya H Jayatissa, Ambalangodage C Jayasuriya

Abstract read
In one paragraph

Article in Journal of biomedical materials research. Part A, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Carbon Nanostructures for Ocular Tissue Reinforcement.Translational vision science & technology · 2022
    Article
  7. Review
  8. Article
  9. Article
  10. Chitosan as an Underrated Polymer in Modern Tissue Engineering.Nanomaterials (Basel, Switzerland) · 2021
    Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. TiORSC advances · 2019
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ashkan AryaeiMechanical Engineering Department, University of Toledo, Toledo, Ohio, 43606.
Ahalapitiya H Jayatissa
Ambalangodage C Jayasuriya

Funding

Dual release of osteogenic factors to enhance bone regenerationR03DE019508 · NIDCR · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI JAYASURIYA, AMBALANGODAGE CHAMPA · 2009 to 2010
$225k
NIDCR NIH HHS DE019508NIDCR NIH HHS R03 DE019508
6 · The paper itself

Abstract

In this article, different concentrations of multiwalled carbon nanotube (MWCNT) were homogeneously dispersed throughout the chitosan (CS) matrix. A simple solvent-cast method was used to fabricate chitosan films with 0.1, 0.5, and 1% of MWCNT with the average diameter around 30 nm. The CS/MWCNT films were characterized for structural, viscous and mechanical properties with optical microscopy, wide-angle X-ray diffraction, Raman spectroscopy, tensile test machine, and microindentation testing machine. Murine osteoblasts were used to examine the cell viability and attachment of the nanocomposite films at two time points. In comparison to the pure chitosan film, the mechanical properties, including the tensile modulus and strength of the films, were greatly improved by increasing the percentage of MWCNT. Furthermore, adding MWCNT up to 1% increased the viscosity of the chitosan solution by 15%. However, adding MWCNT decreased the samples ductility and transparency. In biological point of view, no toxic effect on osteoblasts was observed in the presence of different percentages of MWCNT at day 3 and day 7. This investigation suggested MWCNT could be a promising candidate for improving chitosan mechanical properties without inducing remarkable cytotoxicity on bone cells.

Indexed as

Materials TestingAnimalsCell LineChitosanHardnessHydrogen-Ion ConcentrationInjectionsMechanical PhenomenaMiceNanocompositesNanotubes, CarbonOptical PhenomenaOsteoblastsSpectrum Analysis, RamanTensile StrengthViscosityChitosanNanotubes, Carbonchitosancytotoxicitymechanical propertiesmultiwalled carbon nanotubenanocomposite

Identifiers

PMID24108584
PMCPMC4443444

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.