ArticleThe ISME journal2014
Genetic and functional properties of uncultivated MCG archaea assessed by metagenome and gene expression analyses.
Article in The ISME journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 1 of them a synthesis that pooled it.
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Who cites it
114 citing papers in PubMed, 1 synthesis or guideline pooled it, 298 citations in OpenAlex.
- Pooled it
- Asgard archaea: have we found our microbial ancestors?The EMBO journal · 2026Review
- A dominant subgroup of marine Bathyarchaeia assimilates organic and inorganic carbon into unconventional membrane lipids.Nature microbiology · 2025Article
- Unveiling the life of archaea in sediments: Diversity, metabolic potentials, and ecological roles.iMetaOmics · 2025Review
- Carbon metabolic versatility underpins Bathyarchaeia ecological significance across the global deep subsurface.The ISME journal · 2025Review
- Structures of Saccharolobus solfataricus initiation complexes with leaderless mRNAs highlight archaeal features and eukaryotic proximity.Nature communications · 2025Article
- Adaptation of Archaeal Communities to Summer Hypoxia in the Sediment of Bohai Sea.Ecology and evolution · 2025Article
- Microbial diversity and biogeochemical interactions in the seismically active and COEnvironmental microbiome · 2024Article
- The dynamic history of prokaryotic phyla: discovery, diversity and division.International journal of systematic and evolutionary microbiology · 2024Review
- Anaerobic hexadecane degradation by a thermophilic Hadarchaeon from Guaymas Basin.The ISME journal · 2024Article
- Vertical segregation and phylogenetic characterization of archaea and archaeal ammonia monooxygenase gene in the water column of the western Arctic Ocean.Extremophiles : life under extreme conditions · 2023Article
- Long-read assembled metagenomic approaches improve our understanding on metabolic potentials of microbial community in mangrove sediments.Microbiome · 2023Article
- Taxonomic and carbon metabolic diversification of Bathyarchaeia during its coevolution history with early Earth surface environment.Science advances · 2023Article
- Anaerobic degradation of organic carbon supports uncultured microbial populations in estuarine sediments.Microbiome · 2023Article
- Abundance, classification and genetic potential of Thaumarchaeota in metagenomes of European agricultural soils: a meta-analysis.Environmental microbiome · 2023Article
- Thermal Selection of Microbial Communities and Preservation of Microbial Function in Guaymas Basin Hydrothermal Sediments.Applied and environmental microbiology · 2023Article
- Diverse Bathyarchaeotal Lineages Dominate Archaeal Communities in the Acidic Dajiuhu Peatland, Central China.Microbial ecology · 2023Article
- Phenotypic and genomic characterization ofFrontiers in microbiology · 2023Article
- Article
- Metabolic versatility ofFrontiers in microbiology · 2023Article
54 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Miscellaneous Crenarchaeota group (MCG) Archaea is one of the predominant archaeal groups in anoxic environments and may have significant roles in the global biogeochemical cycles. However, no isolate of MCG has been cultivated or characterized to date. In this study, we investigated the genetic organization, ecophysiological properties and evolutionary relationships of MCG archaea with other archaeal members using metagenome information and the result of gene expression experiments. A comparison of the gene organizations and similarities around the 16S rRNA genes from all available MCG fosmid and cosmid clones revealed no significant synteny among genomic fragments, demonstrating that there are large genetic variations within members of the MCG. Phylogenetic analyses of large-subunit+small-subunit rRNA, concatenated ribosomal protein genes and topoisomerases IB gene (TopoIB) all demonstrate that MCG constituted a sister lineage to the newly proposed archaeal phylum Aigarchaeota and Thaumarchaeota. Genes involved in protocatechuate degradation and chemotaxis were found in a MCG fosmid 75G8 genome fragment, suggesting that this MCG member may have a role in the degradation of aromatic compounds. Moreover, the expression of a putative 4-carboxymuconolactone decarboxylase was observed when the sediment was supplemented with protocatechuate, further supporting the hypothesis that this MCG member degrades aromatic compounds.
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Registered trials
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