ArticleScientific reports2013
Live pigs produced from genome edited zygotes.
Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
78 citing papers in PubMed.
- Gene Editing for Enhanced Swine Production: Current Advances and Prospects.Animals : an open access journal from MDPI · 2025Review
- Genome editing: An insight into disease resistance, production efficiency, and biomedical applications in livestock.Functional & integrative genomics · 2024Review
- The transcriptomic insight into the differential susceptibility of African Swine Fever in inbred pigs.Scientific reports · 2024Article
- Outlook on genome editing application to cattle.Journal of veterinary science · 2024Review
- Current status and future of gene engineering in livestock.BMB reports · 2024Review
- Versatile generation of precise gene edits in bovines using SEGCPN.BMC biology · 2023Article
- Application of Gene Editing Technology in Resistance Breeding of Livestock.Life (Basel, Switzerland) · 2022Review
- The application of new breeding technology based on gene editing in pig industry - A review.Animal bioscience · 2022Article
- Review
- Current status of the application of gene editing in pigs.The Journal of reproduction and development · 2021Review
- Assisted Reproductive Techniques and Genetic Manipulation in the Common Marmoset.ILAR journal · 2020Review
- One-Step Homology Mediated CRISPR-Cas Editing in Zygotes for Generating Genome Edited Cattle.The CRISPR journal · 2020Article
- CRISPR in livestock: From editing to printing.Theriogenology · 2020Review
- Practical Approaches for Knock-Out Gene Editing in Pigs.Frontiers in genetics · 2020Review
- Global developments of genome editing in agriculture.Transgenic research · 2019Article
- Genome editing for disease resistance in pigs and chickens.Animal frontiers : the review magazine of animal agriculture · 2019Article
- Review
- Programmable Molecular Scissors: Applications of a New Tool for Genome Editing in Biotech.Molecular therapy. Nucleic acids · 2019Review
- Production of porcine aminopeptidase N (pAPN) site-specific edited pigs.Animal science journal = Nihon chikusan Gakkaiho · 2019Article
- Harnessing genomic information for livestock improvement.Nature reviews. Genetics · 2019Review
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Transcription activator-like effector nuclease (TALEN) and zinc finger nuclease (ZFN) genome editing technology enables site directed engineering of the genome. Here we demonstrate for the first time that both TALEN and ZFN injected directly into pig zygotes can produce live genome edited pigs. Monoallelic as well as heterozygous and homozygous biallelic events were identified, significantly broadening the use of genome editor technology in livestock by enabling gene knockout in zygotes from any chosen mating.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.