Trial reportAnnals of the rheumatic diseases2015
Self-management approaches for osteoarthritis in the hand: a 2×2 factorial randomised trial.
Trial report in Annals of the rheumatic diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- The prognosis of pain and function in people with hand and thumb base osteoarthritis: a systematic review.Annals of medicine · 2025Pooled it
- Pooled it
- The effects of resistance training on muscle strength, joint pain, and hand function in individuals with hand osteoarthritis: a systematic review and meta-analysis.Arthritis research & therapy · 2017Pooled it
- Exercise for hand osteoarthritis.The Cochrane database of systematic reviews · 2017Pooled it
- Development of the Happy Hands Self-Management App for People with Hand Osteoarthritis: Feasibility Study.JMIR formative research · 2024Trial
- Trial
- The effects of a mobile app-delivered intervention in people with symptomatic hand osteoarthritis: a pragmatic randomized controlled trial.European journal of physical and rehabilitation medicine · 2023Trial
- Functional consultation and exercises improve grip strength in osteoarthritis of the hand - a randomised controlled trial.Arthritis research & therapy · 2018Trial
- Assistive devices: an effective strategy in non-pharmacological treatment for hand osteoarthritis-randomized clinical trial.Rheumatology international · 2018Trial
- A nurse-led clinic for patients consulting with osteoarthritis in general practice: development and impact of training in a cluster randomised controlled trial.BMC family practice · 2016Trial
- Does occupational therapy reduce the need for surgery in carpometacarpal osteoarthritis? Protocol for a randomized controlled trial.BMC musculoskeletal disorders · 2016Trial
- Joint protection and hand exercises for hand osteoarthritis: an economic evaluation comparing methods for the analysis of factorial trials.Rheumatology (Oxford, England) · 2015Trial
- "How would you handle this?" The impact of embedding early patient and public involvement in a biomechanical computational engineering doctoral research project.Research involvement and engagement · 2025Article
- Current and future advances in practice: practical management of hand osteoarthritis.Rheumatology advances in practice · 2025Review
- Co-development and testing of an extended community pharmacy model of service delivery for managing osteoarthritis: protocol for a sequential, multi-methods study (PharmOA).BMC musculoskeletal disorders · 2024Article
- Improving the Effectiveness of Exercise Therapy for Adults With Knee Osteoarthritis: A Pragmatic Randomized Controlled Trial (BEEP Trial).Archives of rehabilitation research and clinical translation · 2023Article
- Systematic Review of Non-surgical Therapies for Osteoarthritis of the Hand: An Update.European journal of rheumatology · 2023Article
- Complex motions embedded in a hand exercise regimen - effects on thumb function in participants with carpometacarpal osteoarthritis: A pilot study.Journal of clinical and translational science · 2023Article
- A rapid review and expert identification of the Allied Health Professions' interventions as a contribution to public health outcomes.Public health in practice (Oxford, England) · 2021Review
- Base of thumb osteoarthritis in UK interface services-a cohort and survey-based study to assess current practice.Rheumatology (Oxford, England) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundOsteoarthritis is the leading cause of disability in older adults. Evidence of effectiveness for self-management of hand osteoarthritis is lacking.
methodsIn this randomised, factorial trial, we evaluated the effectiveness of joint protection versus no joint protection, and hand exercise versus no hand exercise in adults, 50 years of age or older, with hand osteoarthritis. Following a population survey (n=12 297), eligible individuals were randomly assigned (1:1:1:1) to: leaflet and advice; joint protection; hand exercise; joint protection plus hand exercise. Joint protection and hand exercises were delivered by nine occupational therapists, over four group sessions. The primary outcome was the OARSI/OMERACT responder criteria at 6 months. Outcomes were collected blind to allocation (3, 6, 12 m). Analysis was by intention to treat.
resultsOf 257 participants randomised (65:62:65:65) (mean age (SD) 66 years (9.1); female 66%) follow-up was 85% at 6 m (n=212). Baseline characteristics and loss to follow-up were similar between groups. There were no reported treatment side effects. At 6 m 33% assigned joint protection were responders compared with 21% with no joint protection (p=0.03). Of those assigned hand exercises, 28% were responders compared with 25% with no exercises (n.s.). Differences in secondary outcomes were not statistically significant, except for improvement in pain self-efficacy with joint protection (3 m p=0.002; 6 m p=0.001; 12 m p=0.03).
conclusionsThese findings show that occupational therapists can support self-management in older adults with hand osteoarthritis, and that joint protection provides an effective intervention for medium term outcome. (Funded by the Arthritis Research UK ISRCTN 33870549).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.