Evidence map›Paper›PMID 24107851›Full record

ArticleKidney international2014

Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference.

Patrick T Murray, Ravindra L Mehta, Andrew Shaw, Claudio Ronco, Zoltan Endre, John A Kellum, Lakhmir S Chawla, Dinna Cruz, Can Ince, Mark D Okusa and 1 more

Open access · greenAbstract readConference ProceedingsConsensus Statement
In one paragraph

Article in Kidney international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 203 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
203citing papers in PubMed, 7 pooled it
20.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

203 citing papers in PubMed, 7 syntheses or guidelines pooled it, 425 citations in OpenAlex.

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  12. Article
  13. Urinary UDP-sugars provide actionable prediction of acute kidney injury in cardiac surgery patients.American journal of physiology. Heart and circulatory physiology · 2026
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143 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 6 countries.

Patrick T MurrayDepartment of Medicine, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.
Ravindra L MehtaDepartment of Medicine, UCSD Medical Center, University of California San Diego, San Diego, California, USA.
Andrew ShawDepartment of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA.
Claudio RoncoRenal Division, St Bortolo Hospital, International Renal Research Institute, Vicenza, Italy.
Zoltan Endre1] Department of Nephrology, Prince of Wales Clinical School, University of New South Wales, Sydney, New South Wales, Australia [2] Christchurch Kidney Research Group, Department of Medicine, University of Otago, Christchurch, New Zealand.
John A KellumDepartment of Critical Care Medicine, School of Medicine, Pittsburgh, Pennsylvania, USA.
Lakhmir S ChawlaDepartment of Anesthesiology and Critical Care Medicine, George Washington University Medical Center, Washington, DC, USA.
Dinna Cruz1] Department of Nephrology Dialysis and Transplantation, San Bortolo Hospital, Vicenza, Italy [2] International Renal Research Institute (IRRIV), Vicenza, Italy.
Can InceDepartment of Intensive Care Adults, Erasmus MC University Medical Centre Rotterdam, Rotterdam, The Netherlands.
Mark D OkusaDivision of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, University of Virginia, Charlottesville, Virginia, USA.
ADQI 10 workgroup
International Renal Research Institute of Vicenza · ITDuke Medical Center · USErasmus University Rotterdam · NLGeorge Washington University · USUniversity College Dublin · IEUniversity of California San Diego Medical Center · USUniversity of Pittsburgh · USUniversity of Virginia · USUNSW Sydney · AU

Funding

UAB-UCSD O'Brien Core Center for Acute Kidney Injury ResearchP30DK079337 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SANDERS, PAUL W. · 2008 to 2022
$18.3M
Leukocyte Trafficking in Acute Renal FailureR01DK062324 · NIDDK · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI OKUSA, MARK DOUGLAS · 2003 to 2016
$4.4M
NIDDK NIH HHS P30 DK079337NIDDK NIH HHS R01 DK062324
6 · The paper itself

Abstract

Over the last decade there has been considerable progress in the discovery and development of biomarkers of kidney disease, and several have now been evaluated in different clinical settings. Although there is a growing literature on the performance of various biomarkers in clinical studies, there is limited information on how these biomarkers would be utilized by clinicians to manage patients with acute kidney injury (AKI). Recognizing this gap in knowledge, we convened the 10th Acute Dialysis Quality Initiative meeting to review the literature on biomarkers in AKI and their application in clinical practice. We asked an international group of experts to assess four broad areas for biomarker utilization for AKI: risk assessment, diagnosis, and staging; differential diagnosis; prognosis and management; and novel physiological techniques including imaging. This article provides a summary of the key findings and recommendations of the group, to equip clinicians to effectively use biomarkers in AKI.

Indexed as

Renal DialysisAcute Kidney InjuryBiomarkersData Interpretation, StatisticalHumansBiomarkers

Identifiers

PMID24107851
PMCPMC4198530
OpenAlexW1970454678

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.