ArticleDNA research : an international journal for rapid publication of reports on genes and genomes2014
High-resolution linkage and quantitative trait locus mapping aided by genome survey sequencing: building up an integrative genomic framework for a bivalve mollusc.
Article in DNA research : an international journal for rapid publication of reports on genes and genomes, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 145 citations in OpenAlex.
- Genetic Pattern and Diversity of Barbatia virescens: A RAD-Seq Analysis of Five Geographically Distributed Populations.Biochemical genetics · 2026Article
- Article
- Molecular insights into insulin-like signaling and its positive role in growth of the bivalveMarine life science & technology · 2026Article
- Genome refinement in Pacific bluefin tuna (Thunnus orientalis): chromosome-level assembly using hybrid linkage data.BMC genomics · 2026Article
- Predominantly Independent Genetic Control Between Growth and Visceral White Nodules Disease Resistance Revealed by High-Density Linkage Map and QTL Mapping inInternational journal of molecular sciences · 2026Article
- Analysis of Elimination Effects of Inbreeding on Genotype Frequency in Larval Stages of Chinese Shrimp.Biology · 2024Article
- A chromosome-level genome for the nudibranch gastropod Berghia stephanieae helps parse clade-specific gene expression in novel and conserved phenotypes.BMC biology · 2024Article
- Genomic selection for resistance to one pathogenic strain ofFrontiers in genetics · 2024Article
- Fine mapping of the Cepaea nemoralis shell colour and mid-banded loci using a high-density linkage map.Heredity · 2023Article
- Construction of a high-density genetic linkage map and QTL mapping of growth and cold tolerance traits in Takifugu fasciatus.BMC genomics · 2023Article
- Ancient homomorphy of molluscan sex chromosomes sustained by reversible sex-biased genes and sex determiner translocation.Nature ecology & evolution · 2022Article
- The first high-density genetic map of common cockle (Cerastoderma edule) reveals a major QTL controlling shell color variation.Scientific reports · 2022Article
- Mantle Transcriptome Provides Insights into Biomineralization and Growth Regulation in the Eastern Oyster (Crassostrea virginica).Marine biotechnology (New York, N.Y.) · 2022Article
- Identification of quantitative trait loci associated with upper temperature tolerance in turbot, Scophthalmus maximus.Scientific reports · 2021Article
- Genetic Linkage and Physical Mapping for an Oyster Mushroom (Applied and environmental microbiology · 2021Article
- Genome survey and high-resolution genetic map provide valuable genetic resources for Fenneropenaeus chinensis.Scientific reports · 2021Article
- Genome-Wide Association Study RevealsFrontiers in genetics · 2021Article
- Sexual Development of the Hermaphroditic ScallopFrontiers in cell and developmental biology · 2021Article
- Segregation distortion: high genetic load suggested by a Chinese shrimp family under high-intensity selection.Scientific reports · 2020Article
- Adaptive venom evolution and toxicity in octopods is driven by extensive novel gene formation, expansion, and loss.GigaScience · 2020Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic linkage maps are indispensable tools in genetic and genomic studies. Recent development of genotyping-by-sequencing (GBS) methods holds great promise for constructing high-resolution linkage maps in organisms lacking extensive genomic resources. In the present study, linkage mapping was conducted for a bivalve mollusc (Chlamys farreri) using a newly developed GBS method-2b-restriction site-associated DNA (2b-RAD). Genome survey sequencing was performed to generate a preliminary reference genome that was utilized to facilitate linkage and quantitative trait locus (QTL) mapping in C. farreri. A high-resolution linkage map was constructed with a marker density (3806) that has, to our knowledge, never been achieved in any other molluscs. The linkage map covered nearly the whole genome (99.5%) with a resolution of 0.41 cM. QTL mapping and association analysis congruously revealed two growth-related QTLs and one potential sex-determination region. An important candidate QTL gene named PROP1, which functions in the regulation of growth hormone production in vertebrates, was identified from the growth-related QTL region detected on the linkage group LG3. We demonstrate that this linkage map can serve as an important platform for improving genome assembly and unifying multiple genomic resources. Our study, therefore, exemplifies how to build up an integrative genomic framework in a non-model organism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.