ReviewFrontiers in human neuroscience2013
What about the "Self" is Processed in the Posterior Cingulate Cortex?
Review in Frontiers in human neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
144 citing papers in PubMed, 5 syntheses or guidelines pooled it, 260 citations in OpenAlex.
- The convergent neuroscience of Christian prayer and attachment relationships in the context of mental health: a systematic review.Frontiers in psychology · 2025Pooled it
- Do mindfulness-based interventions change brain function in people with substance dependence? A systematic review of the fMRI evidence.BMC psychiatry · 2023Pooled it
- Resting-state abnormalities in Autism Spectrum Disorders: A meta-analysis.Scientific reports · 2019Pooled it
- The anticipation and outcome phases of reward and loss processing: A neuroimaging meta-analysis of the monetary incentive delay task.Human brain mapping · 2018Pooled it
- Beyond emotions: A meta-analysis of neural response within face processing system in social anxiety.Experimental biology and medicine (Maywood, N.J.) · 2016Pooled it
- Changes of cerebral functional connectivity induced by foot reflexology in a RCT.Scientific reports · 2023Trial
- Clinical Efficacy and Psychological Mechanisms of an App-Based Digital Therapeutic for Generalized Anxiety Disorder: Randomized Controlled Trial.Journal of medical Internet research · 2021Trial
- Quitting starts in the brain: a randomized controlled trial of app-based mindfulness shows decreases in neural responses to smoking cues that predict reductions in smoking.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Trial
- Brain activity sustaining the modulation of pain by empathetic comments.Scientific reports · 2019Trial
- Mindfulness-based training attenuates insula response to an aversive interoceptive challenge.Social cognitive and affective neuroscience · 2016Trial
- Maternal Depression, Childhood Resting-State Brain Connectivity, and Adolescent Depression During the COVID-19 Outbreak.Developmental psychobiology · 2026Article
- Shared and unique neural correlates of reappraisal generation and implementation.Cognitive, affective & behavioral neuroscience · 2026Article
- Generating Biologically Relevant Subtypes of Autism Spectrum Disorder with differential responses to Acute Oxytocin Administration in a Randomized Trial using Random Forest Models and K-means Clustering.medRxiv : the preprint server for health sciences · 2026Article
- Altered cortical alpha modulations and connectivity in complex regional pain syndrome.The journal of pain · 2026Article
- Hierarchical systems in the default mode network when reasoning about self and other mental states.Social cognitive and affective neuroscience · 2026Article
- Distinct information flows for different whole-body actions across LOTC subdivisions.Communications biology · 2025Article
- Associations of Prenatal Social Support in Adolescent Mothers With Measures of Social-Emotional Development in Their Young Children.Brain and behavior · 2025Article
- Dysregulated responses to stress and alcohol cues in cortico-striatal-limbic regions in social drinkers with early trauma.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Study protocol for a multi-session randomized sham-controlled trial of PCC- and amygdala-targeted neurofeedback for the treatment of PTSD.BMC psychiatry · 2025Article
- Autobiographical Memory: A Scoping Meta-Review of Neuroimaging Data Enlightens the Inconsistencies Between Theory and Experimentation.Brain sciences · 2025Review
84 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the past decade, neuroimaging research has begun to identify key brain regions involved in self-referential processing, most consistently midline structures such as the posterior cingulate cortex (PCC). The majority of studies have employed cognitive tasks such as judgment about trait adjectives or mind wandering, that have been associated with increased PCC activity. Conversely, tasks that share an element of present-centered attention (being "on task"), ranging from working memory to meditation, have been associated with decreased PCC activity. Given the complexity of cognitive processes that likely contribute to these tasks, the specific contribution of the PCC to self-related processes still remains unknown. Building on this prior literature, recent studies have employed sampling methods that more precisely link subjective experience to brain activity, such as real-time fMRI neurofeedback. This recent work suggests that PCC activity may represent a sub-component cognitive process of self-reference - "getting caught up in" one's experience. For example, getting caught up in a drug craving or a particular viewpoint. In this paper, we will review evidence across a number of different domains of cognitive neuroscience that converges in activation and deactivation of the PCC including recent neurophenomenological studies of PCC activity using real-time fMRI neurofeedback.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.