ArticleRespiratory care2014
Utilization of mechanical ventilation for asthma exacerbations: analysis of a national database.
Article in Respiratory care, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- Asthma exacerbation requiring ventilatory support in adults: a 10-year retrospective multicentre cohort study - the ESAVA study.BMJ open respiratory research · 2026Article
- Veno-Venous Extracorporeal Membrane Oxygenation as Rescue Therapy for Near-Fatal Asthma: A Case Report.Cureus · 2026Article
- Intubation duration after general anesthesia for thrombectomy in acute ischemic stroke: a cohort study.Frontiers in neurology · 2026Article
- Management of Asthma and COPD Exacerbations in Adults in the ICU.CHEST critical care · 2025Article
- Article
- Enteral Feeding for Children on Bilevel Positive Pressure Ventilation for Status Asthmaticus.Journal of pediatric intensive care · 2023Article
- Unmet Need for Oral Corticosteroids Use and Exacerbations of Asthma in Primary Care in Taiwan.Biomedicines · 2022Article
- Endotracheal Tube Size Is Associated With Mortality in Patients With Status Asthmaticus.Respiratory care · 2022Article
- The use of non- invasive ventilation in asthma exacerbation - a two year retrospective analysis of outcomes.Journal of community hospital internal medicine perspectives · 2021Article
- Noninvasive Ventilation Use in Critically Ill Patients with Acute Asthma Exacerbations.American journal of respiratory and critical care medicine · 2020Article
- Hypercapnia: An Aggravating Factor in Asthma.Journal of clinical medicine · 2020Review
- Article
- Acute Severe Asthma in Adolescent and Adult Patients: Current Perspectives on Assessment and Management.Journal of clinical medicine · 2019Review
- Pharmacokinetics of Ketamine at Dissociative Doses in an Adult Patient With Refractory Status Asthmaticus Receiving Extracorporeal Membrane Oxygenation Therapy.Clinical therapeutics · 2019Article
- Extracorporeal membrane oxygenation (ECMO) for near-fatal asthma refractory to conventional ventilation.BMJ case reports · 2018Article
- The comparative effectiveness of noninvasive and invasive ventilation in patients with pneumonia.Journal of critical care · 2018Article
- Noninvasive ventilation in life-threatening asthma: A case series.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2017Article
- Validation of Administrative Definitions of Invasive Mechanical Ventilation across 30 Intensive Care Units.American journal of respiratory and critical care medicine · 2016Article
- Outcomes of Noninvasive and Invasive Ventilation in Patients Hospitalized with Asthma Exacerbation.Annals of the American Thoracic Society · 2016Article
- Hospitals' Patterns of Use of Noninvasive Ventilation in Patients With Asthma Exacerbation.Chest · 2016Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe current frequency of noninvasive (NIV) and invasive mechanical ventilation use in asthma exacerbations (AEs) and the relationship to outcomes are unknown.
methodsWe used the Healthcare Cost and Utilization Project Nationwide Inpatient Sample to identify patients discharged with a principal diagnosis of AE. For each discharge, we determined whether NIV or invasive mechanical ventilation was initiated during the first 2 hospital days. Using multivariate logistic regression to adjust for potential confounders, we determined whether use of mechanical ventilation and in-hospital mortality changed between 2000 and 2008.
resultsThe number of AEs increased by 15.8% from 2000 to 2008. The proportion of admissions for which invasive mechanical ventilation was used during the first 2 days decreased from 1.4% in 2000 to 0.73% in 2008, whereas NIV use increased from 0.34% to 1.9%. The adjusted mortality from AEs requiring NIV or invasive mechanical ventilation was unchanged from 2000 to 2008. The hospital stay was also unchanged.
conclusionsThere was a substantial increase in the use of mechanical ventilation, accompanied by a shift from invasive mechanical ventilation to NIV. Although we could not determine the clinical reasons for this increase, hospital stay and mortality were unchanged. A randomized trial is needed to determine whether NIV can improve outcomes in AEs before widespread adoption makes it impossible to conduct such a trial.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.