Evidence map›Paper›PMID 24106198›Full record

ArticleChembiochem : a European journal of chemical biology2013

Deoxyribozyme cascade for visual detection of bacterial RNA.

Yulia V Gerasimova, Evan M Cornett, Emily Edwards, Xiaoli Su, Kyle H Rohde, Dmitry M Kolpashchikov

Abstract read
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. DNA Nanomachine (DNM) Biplex Assay for DifferentiatingInternational journal of molecular sciences · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. DNA Antenna Tile-Associated Deoxyribozyme Sensor with Improved Sensitivity.Chembiochem : a European journal of chemical biology · 2016
    Article
  14. Article
  15. Article
  16. Article
  17. Design of a biochemical circuit motif for learning linear functions.Journal of the Royal Society, Interface · 2014
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yulia V GerasimovaChemistry Department, University of Central Florida, 4000 Central Florida Blvd, Orlando, FL 32816 (USA).
Evan M Cornett
Emily Edwards
Xiaoli Su
Kyle H Rohde
Dmitry M Kolpashchikov

Funding

Nucleic acid analysis using deoxyribozyme technologyR21HG004060 · NHGRI · UNIVERSITY OF CENTRAL FLORIDA · PI KOLPASHCHIKOV, DMITRY MIKHAYLOVICH · 2006 to 2010
$592k
Deoxyribozyme sensor-based diagnostics for Mycobacterium tuberculosisR15AI103880 · NIAID · UNIVERSITY OF CENTRAL FLORIDA · PI KOLPASHCHIKOV, DMITRY MIKHAYLOVICH · 2013 to 2013
$430k
A Binary Probe-Based DNAzyme Cascade for Rapid Detection of MRSA/MSSAR41AI100468 · NIAID · BIODETECTION INSTRUMENTS, INC. · PI KOLPASHCHIKOV, DMITRY MIKHAYLOVICH, SU, XIAOLI · 2012 to 2012
$169k
NHGRI NIH HHS R21 HG004060NIAID NIH HHS 1R41AI100468-01NIAID NIH HHS R15 AI103880NIAID NIH HHS R41 AI100468
6 · The paper itself

Abstract

In the blink of the eye: a cascade of two deoxyribozymes was designed for rapid visual detection of bacterial 16S rRNA. The detection limit is 12.5 ng by the naked eye, with the ability to differentiate between closely related pathogenic and nonpathogenic species.

Indexed as

Colorimetry3,3'-DiaminobenzidineBacteriaBase SequenceDNA, CatalyticHumansMycobacterium tuberculosisOligonucleotidesRNA, BacterialRNA, Ribosomal, 16S3,3'-DiaminobenzidineDNA, CatalyticOligonucleotidesRNA, BacterialRNA, Ribosomal, 16Sbinary deoxyribozymemycobacterium tuberculosisRNA recognitionsensorsvisual assays

Identifiers

PMID24106198
PMCPMC3947428

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.