Evidence map›Paper›PMID 24105999›Full record

ReviewDevelopmental neurobiology2014

Postsynaptic assembly: a role for Wnt signaling.

Eleanna Stamatakou, Patricia C Salinas

Open access · hybridAbstract readReview
In one paragraph

Review in Developmental neurobiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
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  7. A TBR1-K228E Mutation InducesFrontiers in molecular neuroscience · 2019
    Article
  8. Review
  9. Article
  10. Amyloid β synaptotoxicity is Wnt-PCP dependent and blocked by fasudil.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2018
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Eleanna StamatakouDepartment of Cell and Developmental Biology, University College London, London WC1E 6BT, United Kingdom.
Patricia C Salinas
University College London · GB

Funding

Biotechnology and Biological Sciences Research Council BB/E016006/1Medical Research Council MR/J013374/1Wellcome Trust
6 · The paper itself

Abstract

Synapse formation requires the coordinated formation of the presynaptic terminal, containing the machinery for neurotransmitter release, and the postsynaptic side that possesses the machinery for neurotransmitter reception. For coordinated pre- and postsynaptic assembly signals across the synapse are required. Wnt secreted proteins are well-known synaptogenic factors that promote the recruitment of presynaptic components in diverse organisms. However, recent studies demonstrate that Wnts act directly onto the postsynaptic side at both central and peripheral synapses to promote postsynaptic development and synaptic strength. This review focuses on the role of Wnts in postsynaptic development at central synapses and the neuromuscular junction.

Indexed as

Wnt Signaling PathwayAnimalsHumansNeuromuscular JunctionNeurotransmitter AgentsSynapsesSynaptic PotentialsWnt ProteinsNeurotransmitter AgentsWnt Proteinsdendritic spinesexcitatory and inhibitory synapseneuromuscular junctionsynaptic plasticity

Identifiers

PMID24105999
PMCPMC4237178
OpenAlexW1884253317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.