ArticleThorax2014
Hygiene, atopy and wheeze-eczema-rhinitis symptoms in schoolchildren from urban and rural Ecuador.
Article in Thorax, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Geographic Distribution of Human Infections with Zoonotic Ancylostoma ceylanicum and Anthropophilic Hookworms in Ecuador: A Retrospective Analysis of Archived Stool Samples.The American journal of tropical medicine and hygiene · 2024Article
- Understanding and controlling asthma in Latin America: A review of recent research informed by the SCAALA programme.Clinical and translational allergy · 2023Review
- A comparison of experience sampled hay fever symptom severity across rural and urban areas of the UK.Scientific reports · 2023Article
- Delayed acquisition of airway commensals in antibiotic naïve children and its relationship with wheezing in rural Ecuador.Frontiers in allergy · 2023Article
- Article
- Impact of early life geohelminths on wheeze, asthma and atopy in Ecuadorian children at 8 years.Allergy · 2021Observational
- Asthma, rhinitis and eczema symptoms in Quito, Ecuador: a comparative cross-sectional study 16 years after ISAAC.BMJ open respiratory research · 2021Article
- Patterns of allergic sensitization and factors associated with emergence of sensitization in the rural tropics early in the life course: findings of an Ecuadorian birth cohort.Frontiers in allergy · 2021Article
- Measuring urbanicity as a risk factor for childhood wheeze in a transitional area of coastal ecuador: a cross-sectional analysis.BMJ open respiratory research · 2020Article
- Food allergy, airborne allergies, and allergic sensitisation among adolescents living in two disparate socioeconomic regions in Ecuador: A cross-sectional study.The World Allergy Organization journal · 2020Article
- Training intervention to improve hygiene practices in Islamic boarding school in Yogyakarta, Indonesia: A mixed-method study.PloS one · 2020Article
- Prevalence and risk factors for asthma, rhinitis, eczema, and atopy among preschool children in an Andean city.PloS one · 2020Article
- Soil-transmitted helminth parasites and allergy: Observations from Ecuador.Parasite immunology · 2019Review
- Urban vs rural residency and allergy prevalence among adult women: Iowa Women's Health Study.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2018Article
- Hygiene practices: Are they protective factors for eczema symptoms?Immunity, inflammation and disease · 2018Article
- Effect of Early-Life Geohelminth Infections on the Development of Wheezing at 5 Years of Age.American journal of respiratory and critical care medicine · 2018Article
- Is childhood wheeze and asthma in Latin America associated with poor hygiene and infection? A systematic review.BMJ open respiratory research · 2018Article
- Rural to urban migration is associated with increased prevalence of childhood wheeze in a Latin-American city.BMJ open respiratory research · 2017Article
- Rural residence, farming environment, and allergic diseases in Argentinean adolescents.Pediatric pulmonology · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundRural residence is protective against atopy and wheeze-rhinitis-eczema symptoms in developed countries, an effect attributed to farming and poor hygiene exposures. There are few data from developing countries addressing this question. We compared atopy and wheeze-rhinitis-eczema symptoms between urban and rural Ecuador, and explored the effects of farming and poor hygiene exposures.
methodsWe performed cross sectional studies of schoolchildren living in rural and urban Ecuador. Data on symptoms and farming/hygiene exposures were collected by parental questionnaire, atopy by allergen skin prick test reactivity and geohelminth infections by stool examinations.
resultsAmong 2526 urban and 4295 rural schoolchildren, prevalence was: atopy (10.0% vs 12.5%, p=0.06), wheeze (9.4% vs 10.1%, p=0.05), rhinitis (8.1% vs 6.4%, p=0.02) and eczema (5.9% vs 4.7%, p=0.06). A small proportion of symptoms were attributable to atopy (range 3.9-10.7%) with greater attributable fractions for respiratory symptoms observed in urban schoolchildren. Respiratory symptoms were associated with poor hygiene/farming exposures: wheeze with lack of access to potable water; and rhinitis with household pets, no bathroom facilities and contact with large farm animals. Birth order was inversely associated with respiratory symptoms. Area of residence and atopy had few effects on these associations.
conclusionsUrban schoolchildren living in Ecuador have a similar prevalence of atopy, eczema and wheeze but a higher prevalence of rhinitis compared with rural children. Some farming and poor hygiene exposures were associated with an increase in the prevalence of wheeze or rhinitis while birth order was inversely associated with these symptoms.
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