ArticleTranslational psychiatry2013
Altered fusiform connectivity during processing of fearful faces in social anxiety disorder.
Article in Translational psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Resting-State Brain Activity Changes and Their Genetic Correlates in Mild Traumatic Brain Injury.Human brain mapping · 2025Pooled it
- Abnormal neural activation during negative emotion processing in anxiety disorders: a coordinate-based meta-analysis.CNS spectrums · 2024Pooled it
- Cognitive Neural Mechanism of Social Anxiety Disorder: A Meta-Analysis Based on fMRI Studies.International journal of environmental research and public health · 2021Pooled it
- Beyond emotions: A meta-analysis of neural response within face processing system in social anxiety.Experimental biology and medicine (Maywood, N.J.) · 2016Pooled it
- Predicting pediatric anxiety from the temporal pole using neural responses to emotional faces.Scientific reports · 2021Trial
- Self-referential processing during observation of a speech performance task in social anxiety disorder from pre- to post-treatment: Evidence of disrupted neural activation.Psychiatry research. Neuroimaging · 2019Trial
- Treatment for social anxiety disorder alters functional connectivity in emotion regulation neural circuitry.Psychiatry research. Neuroimaging · 2017Trial
- Normalizing effect of heroin maintenance treatment on stress-induced brain connectivity.Brain : a journal of neurology · 2015Trial
- Epidemiology, genetics, neuroimaging, clinical features, and treatment between overall and performance-only social anxiety disorder: a narrative review.Dialogues in clinical neuroscience · 2026Review
- Genetic influence on functional brain activation to an affective face matching task: an fMRI twin-study.Translational psychiatry · 2026Article
- Machine learning and individual variability in electrical field characteristics predict tDCS treatment response for anxiety in older adults in the ACT trial.Frontiers in human neuroscience · 2026Article
- Exploring the influence of synaptic density and anxiety on pain perception: evidence from a [11C]UCB-J positron emission tomography imaging study.The international journal of neuropsychopharmacology · 2025Article
- Neural circuit basis of pathological anxiety.Nature reviews. Neuroscience · 2025Review
- A novel strategy for detecting multiple mediators in high-dimensional mediation models.Frontiers in psychiatry · 2025Article
- Gray matter volume alterations in de novo Parkinson's disease: A mediational role in the interplay between sleep quality and anxiety.CNS neuroscience & therapeutics · 2024Article
- Aberrant neural correlates of multisensory processing of audiovisual social cues related to social anxiety: An electrophysiological study.Frontiers in psychiatry · 2023Article
- Integrative Brain Dynamics in Childhood Bullying Victimization: Cognitive and Emotional Convergence Associated With Stress Psychopathology.Frontiers in integrative neuroscience · 2022Review
- Distinct Effects of Social Stress on Working Memory in Obsessive-Compulsive Disorder.Neuroscience bulletin · 2021Article
- Restricted Visual Scanpaths During Emotion Recognition in Childhood Social Anxiety Disorder.Frontiers in psychiatry · 2021Article
- Brain structure correlates of expected social threat and reward.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Social anxiety disorder (SAD) has been associated with hyper-reactivity in limbic brain regions like the amygdala, both during symptom provocation and emotional face processing tasks. In this functional magnetic resonance imaging study we sought to examine brain regions implicated in emotional face processing, and the connectivity between them, in patients with SAD (n=14) compared with healthy controls (n=12). We furthermore aimed to relate brain reactivity and connectivity to self-reported social anxiety symptom severity. SAD patients exhibited hyper-reactivity in the bilateral fusiform gyrus in response to fearful faces, as well as greater connectivity between the fusiform gyrus and amygdala, and decreased connectivity between the fusiform gyrus and ventromedial prefrontal cortex. Within the SAD group, social anxiety severity correlated positively with amygdala reactivity to emotional faces, amygdala-fusiform connectivity and connectivity between the amygdala and superior temporal sulcus (STS). These findings point to a pivotal role for the fusiform gyrus in SAD neuropathology, and further suggest that altered amygdala-fusiform and amygdala-STS connectivity could underlie previous findings of aberrant socio-emotional information processing in this anxiety disorder.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.