ReviewNature reviews. Neuroscience2013
The neurobiology of psychopathic traits in youths.
Review in Nature reviews. Neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 234 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
234 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Effects of physical exercise on aggressive behavior in children and adolescents: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Emotion Recognition Deficits in Children and Adolescents with Psychopathic Traits: A Systematic Review.Clinical child and family psychology review · 2024Pooled it
- Psychopharmacological treatment of disruptive behavior in youths: systematic review and network meta-analysis.Scientific reports · 2023Pooled it
- Pooled it
- The genetic underpinnings of callous-unemotional traits: A systematic research review.Neuroscience and biobehavioral reviews · 2019Pooled it
- A Systematic Review and Meta-analysis of Neuroimaging in Oppositional Defiant Disorder (ODD) and Conduct Disorder (CD) Taking Attention-Deficit Hyperactivity Disorder (ADHD) Into Account.Neuropsychology review · 2016Pooled it
- Impact VR: Building Socioemotional Resilience in Youth with Conduct Disorder.Prevention science : the official journal of the Society for Prevention Research · 2026Trial
- Trial
- Impact VR: A Socioemotional Intervention for Reducing CU Traits, Conduct Problems, and Aggression in Youth with Conduct Disorder.Research on child and adolescent psychopathology · 2025Trial
- Oxytocin effects on amygdala reactivity to angry faces in males and females with antisocial personality disorder.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Trial
- Callous-Unemotional Traits as an Intervention Target and Moderator of Parent-Child Interaction Therapy-Emotion Development Treatment for Preschool Depression and Conduct Problems.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Trial
- Trial
- From Stable Traits to Dynamic Mechanisms: An Integrative Conceptual Model of Personality and Criminogenic Cognitions in the Incarcerated Population.Behavioral sciences (Basel, Switzerland) · 2026Review
- Psychopathy Facets Differentially Predict Drug- and Alcohol-Related Problems Following Violent Injury.Behavioral sciences (Basel, Switzerland) · 2026Article
- Aberrant Resting-State Functional Connectivity Associated With Callous-Unemotional Traits From Late Childhood Through Late Adolescence.Biological psychiatry global open science · 2026Article
- Heterogeneity in Callous-Unemotional Traits: Early Temperamental and Environmental Risk Factors in a High-Risk Sample.Clinical psychological science : a journal of the Association for Psychological Science · 2026Article
- Psychopathy and Sadism: A Systematic Review of Their Association, Core Dimensions, and Nosological Implications.Cureus · 2026Review
- Identifying prospective temperament predictors of callous-unemotional traits using machine learning.European child & adolescent psychiatry · 2026Article
- Hippocampal subfield radiomics improves identification of in-hospital aggressive behavior in schizophrenia: an interpretable machine-learning study.BMC psychiatry · 2026Article
- Do Children with High Callous-Unemotional Traits Have Attentional Deficits to Emotional Stimuli? Evidence from a Multi-Method and Multi-Informant Study.Child psychiatry and human development · 2026Article
174 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Conduct disorder is a childhood behaviour disorder that is characterized by persistent aggressive or antisocial behaviour that disrupts the child's environment and impairs his or her functioning. A proportion of children with conduct disorder have psychopathic traits. Psychopathic traits consist of a callous-unemotional component and an impulsive-antisocial component, which are associated with two core impairments. The first is a reduced empathic response to the distress of other individuals, which primarily reflects reduced amygdala responsiveness to distress cues; the second is deficits in decision making and in reinforcement learning, which reflects dysfunction in the ventromedial prefrontal cortex and striatum. Genetic and prenatal factors contribute to the abnormal development of these neural systems, and social-environmental variables that affect motivation influence the probability that antisocial behaviour will be subsequently displayed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.