Evidence map›Paper›PMID 24105322›Full record

ReviewNature reviews. Molecular cell biology2013

RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts.

Sarah Geisler, Jeff Coller

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Molecular cell biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 818 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
818citing papers in PubMed, 2 pooled it
32.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

818 citing papers in PubMed, 2 syntheses or guidelines pooled it, 1,537 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Tuning epigenetics to enhance cancer virotherapy.Acta pharmaceutica Sinica. B · 2026
    Review
  6. ThebioRxiv : the preprint server for biology · 2026
    Article
  7. Review
  8. Rapid turnover of sex-determining architecture in invasive mussels.bioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. LncRNA Knockdown Using Gapmer Antisense Oligonucleotides.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  20. Review

758 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sarah Geisler1] Center for RNA Molecular Biology, Case Western Reserve University, Cleveland, Ohio 44106, USA. [2] Department of Biosystems Science and Engineering, Eidgenössische Technische Hochschule (ETH) Zürich, 4058 Basel, Switzerland.
Jeff Coller
Case Western Reserve University · US

Funding

GRADUATE TRAINING IN CELLULAR AND MOLECULAR BIOLOGYT32GM008056 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI DIEHL, JOHN ALAN, SNIDER, MARTIN D · 1985 to 2019
$7.1M
Understanding the interconnection between mRNA turnover and mRNA translationR01GM080465 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI COLLER, JEFFERY · 2007 to 2016
$2.7M
NIGMS NIH HHS GM080465NIGMS NIH HHS R01 GM080465NIGMS NIH HHS T32 GM008056
6 · The paper itself

Abstract

The increased application of transcriptome-wide profiling approaches has led to an explosion in the number of documented long non-coding RNAs (lncRNAs). While these new and enigmatic players in the complex transcriptional milieu are encoded by a significant proportion of the genome, their functions are mostly unknown. Early discoveries support a paradigm in which lncRNAs regulate transcription via chromatin modulation, but new functions are steadily emerging. Given the biochemical versatility of RNA, lncRNAs may be used for various tasks, including post-transcriptional regulation, organization of protein complexes, cell-cell signalling and allosteric regulation of proteins.

Indexed as

AnimalsGenetic VariationHumansModels, BiologicalRNA, Long NoncodingRNA, Long Noncoding

Identifiers

PMID24105322
PMCPMC4852478
OpenAlexW2093404711

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.