ArticleBritish journal of cancer2013
High-risk features in radiation-associated breast angiosarcomas.
Article in British journal of cancer, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Radiation-induced angiosarcoma of the breast: individual participant meta-analysis of Japanese population.Breast cancer (Tokyo, Japan) · 2023Pooled it
- Primary and secondary breast angiosarcoma: single center report and a meta-analysis.Breast cancer research and treatment · 2019Pooled it
- Radiogenic angiosarcoma of the breast: case report and systematic review of the literature.BMC cancer · 2018Pooled it
- Immune cell clustering identifies a CD163⁺/CSF1R⁺ macrophage and neutrophil-enriched phenotype with distinct biological signatures and poor prognosis in angiosarcoma.Oncoimmunology · 2026Article
- Improved Oncologic Outcomes with Trimodality Therapy for Radiation-Associated Angiosarcoma of the Breast.Annals of surgical oncology · 2026Article
- Recurrent radiogenic angiosarcoma of the breast: a rare case report.International journal of surgery case reports · 2026Article
- Prognostic Factors and Outcomes for Post-Radiation Sarcoma-A Systematic Review and Meta-Analysis.Cancers · 2026Review
- Angiosarcoma in a soft tissue sarcoma cohort: real-world patterns and outcomes.Frontiers in oncology · 2026Article
- Radiation-induced angiosarcoma of the breast: retrospective analysis at a regional treatment centre.Breast cancer (Tokyo, Japan) · 2024Article
- A rare case of radiation-induced breast angiosarcoma: a case report.Case reports in plastic surgery & hand surgery · 2024Article
- Clinicopathological analysis and prognostic treatment study of angiosarcoma of the breast: a SEER population-based analysis.World journal of surgical oncology · 2023Article
- Low Radiologic Sensitivity in Detecting Radiation-Associated Breast Angiosarcoma (RAS).Cureus · 2023Article
- Clinico-demographic characteristics and outcomes of radiation-induced sarcomas (RIS): a CanSaRCC study.Therapeutic advances in medical oncology · 2023Article
- Histology-Specific Prognostication for Radiation-Associated Soft Tissue Sarcoma.JCO precision oncology · 2022Article
- Clinical Impact of Systemic Staging Studies in Secondary Breast Angiosarcoma.Surgery in practice and science · 2022Article
- Clinical and Molecular Insights of Radiation-Induced Breast Sarcomas: Is There Hope on the Horizon for Effective Treatment of This Aggressive Disease?International journal of molecular sciences · 2022Review
- Hyperfractionated-Accelerated Reirradiation with Proton Therapy for Radiation-Associated Breast Angiosarcoma.International journal of particle therapy · 2022Article
- Radiation-induced angiosarcoma: case report.Einstein (Sao Paulo, Brazil) · 2020Article
- Mammography and MRI manifestations of breast angiosarcoma.BMC women's health · 2019Article
- Nothing is impossible: radiation induced angiosarcoma of breast in a male patient.Journal of surgical case reports · 2019Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundRadiation-associated breast angiosarcoma (RT-AS) is an uncommon malignancy with an incidence of less than 1 % of all soft tissue sarcomas. The overall prognosis is quite dismal with high rates of recurrences and poor overall survival. There is an obvious paucity of data regarding clinical outcomes of patients with breast RT-AS.
methodsWe identified all patients with RT-AS treated at the Memorial Sloan-Kettering Cancer Center between 1982-2011 and collected their correlative clinical information.
resultsWe identified 79 women with RT-AS with a median age of 68 (range 36-87). The median interval between radiation and development of RT-AS was 7 years (range 3-19). The median time to local and distant recurrence was 1.29 years (95 % CI 0.72-NA) and 2.48 years (95 % CI 1.29-NA), respectively. The median disease-specific survival was 2.97 years (95 % CI 2.21-NA). Independent predictors of worse disease-specific survival included age 68 years (HR 3.11, 95 % CI 1.20-8.08, P=0.020) and deep tumors (HR 3.23, 95 % CI 1.02-10.21, P=0.046.)
conclusionRT-AS has high local/distant recurrence rates, limited duration on standard chemotherapy and poor disease-specific survival.
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