ArticleNature communications2013
A substantial prehistoric European ancestry amongst Ashkenazi maternal lineages.
Article in Nature communications, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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Who cites it
45 citing papers in PubMed.
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- TERT c.3150 G > C (p.K1050N): a founder Ashkenazi Jewish variant associated with telomere biology disorders.NPJ genomic medicine · 2025Article
- Tracing human genetic histories and natural selection with precise local ancestry inference.Nature communications · 2025Article
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- Global distribution of functionally important CYP2C9 alleles and their inferred metabolic consequences.Human genomics · 2023Article
- Genome-wide data from medieval German Jews show that the Ashkenazi founder event pre-dated the 14Cell · 2022Article
- Genetic and phylogeographic evidence for Jewish Holocaust victims at the Sobibór death camp.Genome biology · 2021Article
- Middle eastern genetic legacy in the paternal and maternal gene pools of Chuetas.Scientific reports · 2020Article
- Spectrum of genes for inherited hearing loss in the Israeli Jewish population, including the novel human deafness gene ATOH1.Clinical genetics · 2020Article
- Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases.International journal of legal medicine · 2020Article
- Rare human mitochondrial HV lineages spread from the Near East and Caucasus during post-LGM and Neolithic expansions.Scientific reports · 2019Article
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- Mitochondrial DNA variability of the Polish population.European journal of human genetics : EJHG · 2019Article
- Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry.JAMA network open · 2019Article
- A western route of prehistoric human migration from Africa into the Iberian Peninsula.Proceedings. Biological sciences · 2019Article
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17 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The origins of Ashkenazi Jews remain highly controversial. Like Judaism, mitochondrial DNA is passed along the maternal line. Its variation in the Ashkenazim is highly distinctive, with four major and numerous minor founders. However, due to their rarity in the general population, these founders have been difficult to trace to a source. Here we show that all four major founders, ~40% of Ashkenazi mtDNA variation, have ancestry in prehistoric Europe, rather than the Near East or Caucasus. Furthermore, most of the remaining minor founders share a similar deep European ancestry. Thus the great majority of Ashkenazi maternal lineages were not brought from the Levant, as commonly supposed, nor recruited in the Caucasus, as sometimes suggested, but assimilated within Europe. These results point to a significant role for the conversion of women in the formation of Ashkenazi communities, and provide the foundation for a detailed reconstruction of Ashkenazi genealogical history.
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