Evidence map›Paper›PMID 24104781›Full record

Observational studyObstetrics and gynecology2013

Twenty-four-month continuation of reversible contraception.

Micaela O'Neil-Callahan, Jeffrey F Peipert, Qiuhong Zhao, Tessa Madden, Gina Secura

Registry-linked trialOpen access · greenAbstract readComparative StudyObservational Study
In one paragraph

Observational study in Obstetrics and gynecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01986439 (The Contraceptive Choice Project), which is not on this map. Cited by 58 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 5 pooled it
28.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01986439 unknown statusnot on this map

The Contraceptive Choice Project

TypeobservationalSponsorEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Ran2007 to 2016Enrolled9,256ConditionsUnintended Pregnancy, Teen Births, Abortion, Contraception
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 5 syntheses or guidelines pooled it, 195 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Pooled it
  4. Family Planning Reminder Systems: An Updated Systematic Review.American journal of preventive medicine · 2018
    Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Long-Acting Reversible Contraception Counseling and Use for Older Adolescents and Nulliparous Women.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2016
    Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Micaela O'Neil-CallahanDivision of Clinical Research, Department of Obstetrics and Gynecology, Washington University in St. Louis School of Medicine, St. Louis, Missouri.
Jeffrey F Peipert
Qiuhong Zhao
Tessa Madden
Gina Secura
Washington University in St. Louis · USEunice Kennedy Shriver National Institute of Child Health and Human Development · US

Funding

Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Washington University Institute of Clinical and Translational SciencesKL2TR000450 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$8.8M
Washington University Institute of Clinical and Translational Sciences (KL2)KL2RR024994 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$8.6M
Washington University Institute of Clinical and Translational SciencesTL1TR000449 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$2.5M
MIDCAREER INVESTIGATOR AWARD IN WOMEN'S HEALTH RESEARCHK24HD001298 · NICHD · WOMEN AND INFANTS HOSPITAL-RHODE ISLAND · PI PEIPERT, JEFFREY FRANK · 2000 to 2009
$1.1M
EVALUATION AND TESTING OF A DECISION SUPPORT AID IN CONTRACEPTIVE DECISION MAKINGK23HD070979 · NICHD · WASHINGTON UNIVERSITY · PI MADDEN, TESSA · 2012 to 2014
$367k
NCATS NIH HHS KL2 TR000450NCATS NIH HHS TL1 TR000449NCATS NIH HHS UL1 TR000448NCRR NIH HHS KL2 RR024994NCRR NIH HHS KL2RR024994NCRR NIH HHS UL1 RR024992NCRR NIH HHS UL1RR024992NICHD NIH HHS K23 HD070979NICHD NIH HHS K23HD070979NICHD NIH HHS K24 HD001298NICHD NIH HHS K24 HD01298
6 · The paper itself

Abstract

objectiveTo estimate 24-month continuation rates of all reversible contraceptive methods for women enrolled in the Contraceptive CHOICE Project.

methodsWe analyzed 24-month data from the 9,256 participants enrolled in the Contraceptive CHOICE Project, a prospective observational cohort study that provides no-cost contraception to women in the St. Louis region. The project promoted the use of long-acting reversible contraception (LARC) (intrauterine devices [IUDs] and implants) in an effort to reduce the rates of unintended pregnancy. This analysis includes participants who received their baseline contraceptive method within 3 months of enrollment and who completed a 24-month follow-up survey (N=6,153).

resultsTwenty-four month continuation rates for long-acting reversible contraception and non-LARC methods were 77% and 41%, respectively. Continuation rates for the levonorgestrel and the copper IUDs were similar (79% compared with 77%), whereas the implant continuation rate was significantly lower (69%, P<.001) compared with IUDs at 24 months. There was no statistically significant difference in 24-month continuation rates among the four non-LARC methods (oral contraceptive pill [OCP] 43%, patch 40%, ring 41%, depot medroxyprogesterone acetate [DMPA] 38%; P=.72). Participants who chose a LARC method at enrollment were at significantly lower risk of contraceptive method discontinuation (adjusted hazard ratio 0.29, 95% confidence interval 0.26-0.32) compared with women who selected a non-LARC method.

conclusionIntrauterine devices and the implant have the highest rates of continuation at 24 months. Given their effectiveness and high continuation rates, IUDs and implants should be first-line contraceptive options and shorter-acting methods such as OCPs, patch, ring, and DMPA should be second tier. LEVEL OF EVIDENCE: II.

Indexed as

AdolescentAdultBody Mass IndexCohort StudiesContraceptionContraceptive Agents, FemaleContraceptives, OralFemaleFollow-Up StudiesHumansInterviews as TopicIntrauterine DevicesIntrauterine Devices, CopperLevonorgestrelMedroxyprogesterone AcetateParityContraceptive Agents, FemaleContraceptives, OralLevonorgestrelMedroxyprogesterone Acetate

Identifiers

PMID24104781
PMCPMC4012225
OpenAlexW1989685346

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.