Evidence map›Paper›PMID 24104771›Full record

ArticleObstetrics and gynecology2013

Development of a comorbidity index for use in obstetric patients.

Brian T Bateman, Jill M Mhyre, Sonia Hernandez-Diaz, Krista F Huybrechts, Michael A Fischer, Andreea A Creanga, William M Callaghan, Joshua J Gagne

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Obstetrics and gynecology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05704179 (Evaluation of the Relationship Between Obstetric Comorbidity Index and Obstetric Recovery Quality Score in Patients Who Undergo Operative Delivery), which is not on this map. Cited by 230 papers.

0numbers the graph read from it
0cells of the map it votes in
230citing papers in PubMed
10.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05704179 completednot on this mapstarted 2023, after this paper: background citation

Evaluation of the Relationship Between Obstetric Comorbidity Index and Obstetric Recovery Quality Score in Patients Who Undergo Operative Delivery

TypeobservationalSponsorProf. Dr. Cemil Tascıoglu Education and Research Hospital OrganizationRan2023 to 2023Enrolled214ConditionsQuality of Life, Obstetric Complication, Cesarean Section Complications, Comorbidities and Coexisting ConditionsArmsObstetric Quality of recovery score
3 · Its place in the literature

Who cites it

230 citing papers in PubMed, 479 citations in OpenAlex.

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  2. Associations between maternal sleep disorders and long-term neurodevelopmental disorders in children: evidence from a national cohort of 1.9 million births.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
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170 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Brian T BatemanDivision of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, the Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, and the Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts; the Department of Anesthesiology, University of Michigan Health System, Ann Arbor, Michigan; and the Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia.
Jill M Mhyre
Sonia Hernandez-Diaz
Krista F Huybrechts
Michael A Fischer
Andreea A Creanga
William M Callaghan
Joshua J Gagne
Harvard University · USBrigham and Women's Hospital · USMassachusetts General Hospital · USThe Centers · US

Funding

Comparative Effectiveness and Safety of Depression Treatments during PregnancyR01HS018533 · AHRQ · HARVARD SCHOOL OF PUBLIC HEALTH · PI HERNANDEZ-DIAZ, SONIA · 2009 to 2013
$2.2M
Comparative safety & effectiveness of antihypertensive medications in pregnancyK08HD075831 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI BATEMAN, BRIAN THOMAS · 2013 to 2017
$717k
AHRQ HHS R01 HS018533AHRQ HHS R01HS018533NICHD NIH HHS K08 HD075831NICHD NIH HHS K08HD075831
6 · The paper itself

Abstract

objectiveTo develop and validate a maternal comorbidity index to predict severe maternal morbidity, defined as the occurrence of acute maternal end-organ injury, or mortality.

methodsData were derived from the Medicaid Analytic eXtract for the years 2000-2007. The primary outcome was defined as the occurrence of maternal end-organ injury or death during the delivery hospitalization through 30 days postpartum. The data set was randomly divided into a two-thirds development cohort and a one-third validation cohort. Using the development cohort, a logistic regression model predicting the primary outcome was created using a stepwise selection algorithm that included 24-candidate comorbid conditions and maternal age. Each of the conditions included in the final model was assigned a weight based on its beta coefficient, and these were used to calculate a maternal comorbidity index.

resultsThe cohort included 854,823 completed pregnancies, of which 9,901 (1.2%) were complicated by the primary study outcome. The derived score included 20 maternal conditions and maternal age. For each point increase in the score, the odds ratio for the primary outcome was 1.37 (95% confidence interval [CI] 1.35-1.39). The c-statistic for this model was 0.657 (95% CI 0.647-0.666). The derived score performed significantly better than available comorbidity indices in predicting maternal morbidity and mortality.

conclusionThis new maternal comorbidity index provides a simple measure for summarizing the burden of maternal illness for use in the conduct of epidemiologic, health services, and comparative effectiveness research. LEVEL OF EVIDENCE: II.

Indexed as

Severity of Illness IndexAcute DiseaseAdolescentAdultCohort StudiesComorbidityDelivery, ObstetricDisseminated Intravascular CoagulationFemaleHeart FailureHumansLogistic ModelsMedicaidMiddle AgedPostpartum PeriodPregnancy

Identifiers

PMID24104771
PMCPMC3829199
OpenAlexW2005569714

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.