Evidence map›Paper›PMID 24104210›Full record

ReviewProgress in retinal and eye research2013

Using human induced pluripotent stem cells to treat retinal disease.

S Borooah, M J Phillips, B Bilican, A F Wright, I Wilmut, S Chandran, D Gamm, B Dhillon

Abstract readReview
In one paragraph

Review in Progress in retinal and eye research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Stem cell therapies for retinal diseases: from bench to bedside.Journal of molecular medicine (Berlin, Germany) · 2020
    Review
  8. Recapitulating developmental mechanisms for retinal regeneration.Progress in retinal and eye research · 2020
    Review
  9. Article
  10. Article
  11. Impedance-based cellular assays for regenerative medicine.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. [New biomaterials and alternative stem cell sources for the reconstruction of the limbal stem cell niche].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2017
    Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S BorooahMRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, UK; Ophthalmology, School of Clinical Sciences, University of Edinburgh, Edinburgh EH16 4SB, UK.
M J Phillips
B Bilican
A F Wright
I Wilmut
S Chandran
D Gamm
B Dhillon

Funding

WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI MESSING, ALBEE · 1985 to 2015
$25.2M
Mechanisms of Retinogenesis in Human Stem CellsR01EY021218 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI GAMM, DAVID M · 2010 to 2017
$2.2M
Medical Research Council MC_PC_U127584475Medical Research Council MC_U127584475NEI NIH HHS NIH R01 EY021218NEI NIH HHS R01 EY021218NICHD NIH HHS P30 HD003352Wellcome Trust
6 · The paper itself

Abstract

The eye is an ideal target for exploiting the potential of human induced pluripotent stem cell (hiPSC) technology in order to understand disease pathways and explore novel therapeutic strategies for inherited retinal disease. The aim of this article is to map the pathway from state-of-the art laboratory-based discoveries to realising the translational potential of this emerging technique. We describe the relevance and routes to establishing hiPSCs in selected models of human retinal disease. Additionally, we define pathways for applying hiPSC technology in treating currently incurable, progressive and blinding retinal disease.

Indexed as

HumansInduced Pluripotent Stem CellsModels, BiologicalRegenerative MedicineRetinal DiseasesStem Cell TransplantationiPSPluripotentReprogrammingRetinaStem cells

Identifiers

PMID24104210
PMCPMC3841575

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.