Evidence map›Paper›PMID 24103413›Full record

ArticlePublic health nutrition2014

Prenatal mercury exposure and infant birth weight in the Norwegian Mother and Child Cohort Study.

Kristine Vejrup, Anne Lise Brantsæter, Helle K Knutsen, Per Magnus, Jan Alexander, Helen E Kvalem, Helle M Meltzer, Margaretha Haugen

Open access · bronzeAbstract read
In one paragraph

Article in Public health nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Mercury Exposure in Women of Reproductive Age in Rondônia State, Amazon Region, Brazil.International journal of environmental research and public health · 2023
    Article
  6. Occupational and environmental mercury exposure and human reproductive health - a review.Journal of the Turkish German Gynecological Association · 2022
    Article
  7. Article
  8. Brief Review of Endometriosis and the Role of Trace Elements.International journal of molecular sciences · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Review
  16. Pregnant Inuit Women's Exposure to Metals and Association with Fetal Growth Outcomes: ACCEPT 2010⁻2015.International journal of environmental research and public health · 2019
    Article
  17. Insights into the Potential Role of Mercury in Alzheimer's Disease.Journal of molecular neuroscience : MN · 2019
    Review
  18. Review
  19. Article
  20. Mercury in Children: Current State on Exposure through Human Biomonitoring Studies.International journal of environmental research and public health · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Kristine Vejrup1Division of Epidemiology,Norwegian Institute of Public Health,Post Box 4404 Nydalen,NO-0403 Oslo,Norway.
Anne Lise Brantsæter2Division of Environmental Medicine,Norwegian Institute of Public Health,Oslo,Norway.
Helle K Knutsen2Division of Environmental Medicine,Norwegian Institute of Public Health,Oslo,Norway.
Per Magnus1Division of Epidemiology,Norwegian Institute of Public Health,Post Box 4404 Nydalen,NO-0403 Oslo,Norway.
Jan Alexander3Office of Director-General,Norwegian Institute of Public Health,Oslo,Norway.
Helen E Kvalem2Division of Environmental Medicine,Norwegian Institute of Public Health,Oslo,Norway.
Helle M Meltzer2Division of Environmental Medicine,Norwegian Institute of Public Health,Oslo,Norway.
Margaretha Haugen2Division of Environmental Medicine,Norwegian Institute of Public Health,Oslo,Norway.
Norwegian Institute of Public Health · NOOslo Nye Høyskole · NO

Funding

Gene-Environment Interactions in an Autism Birth CohortU01NS047537 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LIPKIN, W. IAN · 2003 to 2013
$27.0M
NIEHS NIH HHS N01 ES075558NIEHS NIH HHS N01-ES-75558NINDS NIH HHS 1 UO1 NS047537-01NINDS NIH HHS 2 UO1 NS 047537-06A1NINDS NIH HHS U01 NS047537
6 · The paper itself

Abstract

objectiveTo examine the association between calculated maternal dietary exposure to Hg in pregnancy and infant birth weight in the Norwegian Mother and Child Cohort Study (MoBa).

designExposure was calculated with use of a constructed database of Hg in food items and reported dietary intake during pregnancy. Multivariable regression models were used to explore the association between maternal Hg exposure and infant birth weight, and to model associations with small-for-gestational-age offspring.

settingThe study is based on data from MoBa. SUBJECTS: The study sample consisted of 62 941 women who answered a validated FFQ which covered the habitual diet during the first five months of pregnancy.

resultsMedian exposure to Hg was 0·15 μg/kg body weight per week and the contribution from seafood intake was 88 % of total Hg exposure. Women in the highest quintile compared with the lowest quintile of Hg exposure delivered offspring with 34 g lower birth weight (95 % CI -46 g, -22 g) and had an increased risk of giving birth to small-for-gestational-age offspring, adjusted OR = 1·19 (95 % CI 1·08, 1·30). Although seafood intake was positively associated with increased birth weight, stratified analyses showed negative associations between Hg exposure and birth weight within strata of seafood intake.

conclusionsAlthough seafood intake in pregnancy is positively associated with birth weight, Hg exposure is negatively associated with birth weight. Seafood consumption during pregnancy should not be avoided, but clarification is needed to identify at what level of Hg exposure this risk might exceed the benefits of seafood.

Indexed as

Food ContaminationMaternal Nutritional Physiological PhenomenaPrenatal Exposure Delayed EffectsBirth WeightCohort StudiesDatabases, FactualFeeding BehaviorFemaleFetal Growth RetardationHumansInfant, NewbornInfant, Small for Gestational AgeMaleMercuryNorwayPregnancyMercuryWater Pollutants, Chemical

Identifiers

PMID24103413
PMCPMC11108685
OpenAlexW2142025052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.