ArticleThe Libyan journal of medicine2013
Rose geranium essential oil as a source of new and safe anti-inflammatory drugs.
Article in The Libyan journal of medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Effectiveness of Aromatherapy in the Management of Labor Pain and Anxiety: A Systematic Review.Ethiopian journal of health sciences · 2020Pooled it
- Oleogel Dressings for Skin Therapy: Physicochemical and Bioactive Properties of Cosmetic Oil-Based Systems Enriched with Essential Oils.Gels (Basel, Switzerland) · 2026Article
- Gellan gum-based composites hydrogel membranes with geranium and lemongrass oils for enhanced antibacterial and wound healing effect.Scientific reports · 2025Article
- Geranium Oil Nanoemulsion Delivers More Potent and Persistent Fumigant Control ofFoods (Basel, Switzerland) · 2025Article
- The anti-nociceptive and anti-inflammatory effects of Pelargonium graveolens essential oil nanoemulsion in mice.Scientific reports · 2025Article
- Dietary Pelargonium Sidoides extract mitigates thermal stress in Oreochromis niloticus: physiological and immunological insights.Veterinary research communications · 2025Article
- Evaluation of the effectiveness of some essential oils against zoonotic methicillin-resistantJournal of advanced veterinary and animal research · 2024Article
- Natural Sources of Therapeutic Agents Used in Skin Conditions.Life (Basel, Switzerland) · 2024Review
- Exploring the Sustainable Exploitation of Bioactive Compounds inPlants (Basel, Switzerland) · 2023Review
- Antioxidative and Anti-Inflammatory Activities of Rosebud Extracts of Newly Crossbred Roses.Nutrients · 2023Article
- Pingyin rose essential oil alleviates LPS-Induced inflammation in RAW 264.7 cells via the NF-κB pathway: an integrated in vitro and network pharmacology analysis.BMC complementary medicine and therapies · 2022Article
- Tailoring of Geranium Oil-Based Nanoemulsion Loaded with Pravastatin as a Nanoplatform for Wound Healing.Polymers · 2022Article
- Laser Light Treatment Improves the Mineral Composition, Essential Oil Production and Antimicrobial Activity of Mycorrhizal TreatedMolecules (Basel, Switzerland) · 2022Article
- A New Eucalyptol-Rich Lavender (Molecules (Basel, Switzerland) · 2020Article
- Distinct metabolic pathways drive monoterpenoid biosynthesis in a natural population of Pelargonium graveolens.Journal of experimental botany · 2020Article
- Frankincense, pine needle and geranium essential oils suppress tumor progression through the regulation of the AMPK/mTOR pathway in breast cancer.Oncology reports · 2018Article
- Effects of Geranium Aromatherapy Massage on Premenstrual Syndrome: A Clinical Trial.International journal of preventive medicine · 2018Article
- Analgesic-Like Activity of Essential Oil Constituents: An Update.International journal of molecular sciences · 2017Review
- Chemical composition analysis andBiochimie open · 2017Article
- An Overview of the Biological Effects of Some Mediterranean Essential Oils on Human Health.BioMed research international · 2017Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince the available anti-inflammatory drugs exert an extensive variety of side effects, the search for new anti-inflammatory agents has been a priority of pharmaceutical industries.
aimsThe aim of the present study was to assess the anti-inflammatory activities of the essential oil of rose geranium (RGEO).
methodsThe chemical composition of the RGEO was investigated by gas chromatography. The major components were citronellol (29.13%), geraniol (12.62%), and citronellyl formate (8.06%). In the carrageenan-induced paw edema, five different groups were established and RGEO was administered orally in three different doses.
resultsRGEO (100 mg/kg) was able to significantly reduce the paw edema with a comparable effect to that observed with diclofenac, the positive control. In addition, RGEO showed a potent anti-inflammatory activity by topical treatment in the method of croton oil-induced ear edema. When the dose was 5 or 10 µl of RGEO per ear, the inflammation was reduced by 73 and 88%, respectively. This is the first report to demonstrate a significant anti-inflammatory activity of Algerian RGEO. In addition, histological analysis confirmed that RGEO inhibited the inflammatory responses in the skin.
conclusionOur results indicate that RGEO may have significant potential for the development of novel anti-inflammatory drugs with improved safety profile.
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