ArticleEvolution; international journal of organic evolution2014
Strong selection genome-wide enhances fitness trade-offs across environments and episodes of selection.
Article in Evolution; international journal of organic evolution, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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38 citing papers in PubMed.
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- Spatially and temporally varying selection influence species boundaries in two sympatricProceedings. Biological sciences · 2023Article
- Taking quantitative genomics into the wild.Proceedings. Biological sciences · 2022Article
- The genomic scale of fluctuating selection in a natural plant population.Evolution letters · 2022Article
- Local adaptation: Causal agents of selection and adaptive trait divergence.Annual review of ecology, evolution, and systematics · 2022Article
- Utility and challenges of using whole-genome resequencing to detect emerging insect and mite resistance in agroecosystems.Evolutionary applications · 2022Review
- A polygenic architecture with habitat-dependent effects underlies ecological differentiation in Silene.The New phytologist · 2022Article
- Globally Relaxed Selection and Local Adaptation in Boechera stricta.Genome biology and evolution · 2022Article
- Evolution of flowering time in a selfing annual plant: Roles of adaptation and genetic drift.Ecology and evolution · 2022Article
- Identifying loci under selection via explicit demographic models.Molecular ecology resources · 2021Article
- The promise and deceit of genomic selection component analyses.Proceedings. Biological sciences · 2021Article
- Phenotypic plasticity under rapid global changes: The intrinsic force for future seagrasses survival.Evolutionary applications · 2021Review
- The ecological, genetic and genomic architecture of local adaptation and population differentiation inProceedings. Biological sciences · 2021Article
- Fitness maps to a large-effect locus in introduced stickleback populations.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Predicting evolutionary change at the DNA level in a natural Mimulus population.PLoS genetics · 2021Article
- Pleiotropy facilitates local adaptation to distant optima in common ragweed (Ambrosia artemisiifolia).PLoS genetics · 2020Article
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3 authors.
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Abstract
Fitness trade-offs across episodes of selection and environments influence life-history evolution and adaptive population divergence. Documenting these trade-offs remains challenging as selection can vary in magnitude and direction through time and space. Here, we evaluate fitness trade-offs at the levels of the whole organism and the quantitative trait locus (QTL) in a multiyear field study of Boechera stricta (Brassicaceae), a genetically tractable mustard native to the Rocky Mountains. Reciprocal local adaptation was pronounced for viability, but not for reproductive components of fitness. Instead, local genomes had a fecundity advantage only in the high latitude garden. By estimating realized selection coefficients from individual-level data on viability and reproductive success and permuting the data to infer significance, we examined the genetic basis of fitness trade-offs. This analytical approach (Conditional Neutrality-Antagonistic Pleiotropy, CNAP) identified genetic trade-offs at a flowering phenology QTL (costs of adaptation) and revealed genetic trade-offs across fitness components (costs of reproduction). These patterns would not have emerged from traditional ANOVA-based QTL mapping. Our analytical framework can be applied to other systems to investigate fitness trade-offs. This task is becoming increasingly important as climate change may alter fitness landscapes, potentially disrupting fitness trade-offs that took many generations to evolve.
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