Evidence map›Paper›PMID 24102498›Full record

ArticleScandinavian journal of primary health care2013

Different recommendations for empiric first-choice antibiotic treatment of uncomplicated urinary tract infections in Europe.

Josephine McQuiston Haslund, Marianne Rosborg Dinesen, Anni Brit Sternhagen Nielsen, Carl Llor, Lars Bjerrum

Abstract readComparative Study
In one paragraph

Article in Scandinavian journal of primary health care, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Lessons from an 11-year retrospective cohort study ofIranian journal of microbiology · 2024
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  10. Observational
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  14. Review
  15. Trends in Primary Antibiotic Resistance inAntibiotics (Basel, Switzerland) · 2020
    Article
  16. Article
  17. Prevalence of quinolone-resistant uropathogenicInfection and drug resistance · 2019
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Josephine McQuiston HaslundSection and Research Unit of General Practice, Department of Public Health, University of Copenhagen , Denmark.
Marianne Rosborg Dinesen
Anni Brit Sternhagen Nielsen
Carl Llor
Lars Bjerrum

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveUncomplicated urinary tract infection (uUTI) is a common reason for antibiotic treatment in primary health care. Due to the increasing prevalence of antibiotic-resistant uropathogens it is crucial to use the most appropriate antibiotics for first-choice empiric treatment of uUTI. Particularly, it is important to avoid antibiotics associated with a high rate of antimicrobial resistance. This study compares national recommendations from six European countries, investigating recommendations for first-choice antibiotic therapy of uUTI.

settingGeneral practice in six European countries.

methodSearches were undertaken on PubMed, the Cochrane Library databases, Google, and Google Scholar. Recommendations from different geographical regions in Europe were investigated: Northern Europe (Denmark, Sweden), Western Europe (Scotland), Central Europe (Germany), Southern Europe (Spain), and Eastern Europe (Croatia).

resultsThe six countries recommended seven different antibiotics. Five countries recommended more than one antibiotic as first-choice treatment. Half of the countries recommended antibiotics associated with a high rate (> 10-20%) of resistant E. coli. All countries recommended at least one antibiotic associated with a low (< 5%) resistance rate. DISCUSSION: The differences in first-choice treatment of uUTI could not be explained by differences in local bacterial aetiology or by different patterns of antimicrobial resistance. Despite resistance rates exceeding 10-20%, sulphamethizole, trimethoprim. or fluoroquinolones were recommended in half of the countries.

conclusionWithin the European countries there are considerable differences in recommendations for empiric first-choice antibiotic treatment of uUTI. In order to reduce the increasing antimicrobial resistance in Europe, it is important to agree on the most appropriate antibiotics for empiric treatment of uUTI.

Indexed as

Practice Guidelines as TopicAnti-Bacterial AgentsDrug Resistance, BacterialEuropeHumansPractice Patterns, Physicians'Primary Health CareUrinary Tract InfectionsAnti-Bacterial Agents

Identifiers

PMID24102498
PMCPMC3860300

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.