SynthesisWorld journal of surgery2014
Biologic versus nonbiologic mesh in ventral hernia repair: a systematic review and meta-analysis.
Synthesis in World journal of surgery, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 4 syntheses or guidelines pooled it, 128 citations in OpenAlex.
- Meta-analysis of controlled studies comparing biologic and synthetic unabsorbable mesh in contaminated fields.Surgical endoscopy · 2025Pooled it
- A systematic review and meta-analysis of randomized controlled trials for the management of ventral hernia: biologic versus synthetic mesh.Updates in surgery · 2024Pooled it
- Biologic Mesh in Surgery: A Comprehensive Review and Meta-Analysis of Selected Outcomes in 51 Studies and 6079 Patients.World journal of surgery · 2021Pooled it
- Prevention of incisional hernia at the site of stoma closure with different reinforcing mesh types: a systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2021Pooled it
- Comparative Outcomes of Two Non-Crosslinked Porcine Acellular Dermal Matrices in Complex Abdominal Wall Reconstruction: A Randomized Controlled Trial and an Observational Cohort Study.World journal of surgery · 2026Trial
- Trial
- Article
- Absorbable mesh is associated with a higher risk of recurrence and reoperation: a propensity score-matched comparison of mesh performance in clean and contaminated ventral hernia repairs.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Hernia Recurrence Risk Matters More Than Mesh Type to Patients Undergoing Ventral Hernia Repair.The Journal of surgical research · 2025Article
- Use of Biologic and Biosynthetic Mesh for Ventral Hernia Repair in Current Practice.JAMA surgery · 2025Article
- Combined use of composite mesh and acellular dermal matrix graft for abdominal wall repair following tumour resection.World journal of surgical oncology · 2024Article
- Ventral Hernia Reconstruction with GORE ENFORM Biomaterial.Plastic surgery (Oakville, Ont.) · 2024Article
- Comparative long-term effectiveness between ventral hernia repairs with biosynthetic and synthetic mesh.Surgical endoscopy · 2023Review
- Efficient Decellularization of the Full-Thickness Rat-Derived Abdominal Wall to Produce Acellular Biologic Scaffolds for Tissue Reconstruction: Promising Evidence Acquired from In Vitro Results.Bioengineering (Basel, Switzerland) · 2023Article
- Outcomes of Complex Abdominal Wall Reconstruction After Oncologic Resection: 14-Year Experience at an NCI-Designated Cancer Center.Annals of surgical oncology · 2023Article
- Acellular dermal matrix in reconstructive surgery: Applications, benefits, and cost.Frontiers in transplantation · 2023Review
- Reinforced Biologic Mesh Reduces Postoperative Complications Compared to Biologic Mesh after Ventral Hernia Repair.Plastic and reconstructive surgery. Global open · 2022Article
- Abdominal wall complications after kidney transplantation: A clinical review.Clinical transplantation · 2021Review
- Massive traumatic abdominal wall hernia with significant tissue loss: challenges in management.BMJ case reports · 2021Article
- Outcomes of Poly-4-hydroxybutyrate Mesh in Ventral Hernia Repair: A Systematic Review and Pooled Analysis.Plastic and reconstructive surgery. Global open · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe current standard of treatment for most ventral hernias is a mesh-based repair. Little is known about the safety and efficacy of biologic versus nonbiologic grafts. A meta-analysis was performed to examine two primary outcomes: recurrence and wound complication rates.
methodsElectronic databases and reference lists of relevant articles were systematically searched for all clinical trials and cohort studies published between January 1990 and January 2012. A total of eight retrospective studies, with 1,229 patients, were included in the final analysis.
resultsBiologic grafts had significantly fewer infectious wound complications (p < 0.00001). However, the recurrence rates of biologic and nonbiologic mesh were not different. In subgroup analysis, there was no difference in recurrence rates and wound complications between human-derived and porcine-derived biologic grafts.
conclusionsUse of biologic mesh for ventral hernia repair results in less infectious wound complications but similar recurrence rates compared to nonbiologic mesh. This supports the application of biologic mesh for ventral hernia repair in high-risk patients or patients with a previous history of wound infection only when the significant additional cost of these materials can be justified and synthetic mesh is considered inappropriate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.