Evidence map›Paper›PMID 24100725›Full record

ReviewCurrent opinion in gastroenterology2013

Gastroduodenal mucosal defense.

Thomas Kemmerly, Jonathan D Kaunitz

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Thomas KemmerlyaCedars-Sinai Medical Residency Program bGreater Los Angeles Veteran Affairs Healthcare System, WLAVA Medical Center cDepartment of Medicine dDepartment of Surgery, UCLA School of Medicine eCURE: Digestive Diseases Research Center Department of Medicine fBrentwood Biomedical Research Institute, Los Angeles, California, USA.
Jonathan D Kaunitz
Cedars-Sinai Medical Center · USWest Los Angeles College · US

Funding

Duodenal Muscosal Defense MechanismsR01DK054221 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KAUNITZ, JONATHAN D. · 1999 to 2016
$4.4M
Luminal Factors Affecting Duodenal Protection and ChemosensingI01BX001245 · VA · VA GREATER LOS ANGELES HEALTHCARE SYSTEM · PI KAUNITZ, JONATHAN D. · 2012 to 2025
–
BLRD VA I01 BX001245NIDDK NIH HHS R01 DK054221
6 · The paper itself

Abstract

purpose of reviewTo review recent developments in the field of gastroduodenal mucosal defense. RECENT

findingsResearch in the field of gastroduodenal mucosal defense has focused on continued elucidation of molecular mechanisms that protect the mucosa and influence healing at the cellular level. Review of literature over the past year reveals focus on familiar processes such as superoxide dismutase, nitric oxide, heme oxygenase-1, neutrophil infiltration, cysteamine, mucin, hydrogen sulfide, ghrelin, adiponectin and the influence of Helicobacter pylori, but also brings into light new processes such as the balance between apoptosis and cellular proliferation, as well as the influence of other organ systems such as the bone marrow and central nervous system on the gastrointestinal tract. SUMMARY: These new published findings contribute to our overall understanding of gastroduodenal defense and suggest innovative avenues of future research and possible novel therapeutic targets.

Indexed as

ApoptosisCell ProliferationDuodenumGastric MucosaHelicobacter InfectionsHelicobacter pyloriHormonesHumansInflammationIntestinal MucosaMesenchymal Stem CellsMucinsOxidative StressHormonesMucins

Identifiers

PMID24100725
PMCPMC7193727
OpenAlexW4242501894

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.