ArticlePloS one2013
Transcriptomics of the rice blast fungus Magnaporthe oryzae in response to the bacterial antagonist Lysobacter enzymogenes reveals candidate fungal defense response genes.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Experimental validation of emamectin as predicted from the meta-analysis of in planta RNA-Seq data as a potential antifungal agent against Magnaporthe oryzae.World journal of microbiology & biotechnology · 2025Pooled it
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- Coral color morphs exhibit distinct microbial and proteomic profiles linked to stress and immune mechanisms in a changing ocean.Microbiome · 2026Article
- Symbioses between fungi and bacteria: from mechanisms to impacts on biodiversity.Current opinion in microbiology · 2024Review
- Bacterial-fungal interactions under agricultural settings: from physical to chemical interactions.Stress biology · 2022Review
- Evaluating the Mode of Antifungal Action of Heat-Stable Antifungal Factor (HSAF) inJournal of fungi (Basel, Switzerland) · 2022Article
- Cytoplasmic Lipases-A Novel Class of Fungal Defense Proteins Against Nematodes.Frontiers in fungal biology · 2021Article
- Transcriptomic and Ultrastructural Analyses ofFrontiers in microbiology · 2021Article
- Molecular Dialogues between Early Divergent Fungi and Bacteria in an Antagonism versus a Mutualism.mBio · 2020Article
- Combining microfluidics and RNA-sequencing to assess the inducible defensome of a mushroom against nematodes.BMC genomics · 2019Article
- Induction of antibacterial proteins and peptides in the coprophilous mushroom Coprinopsis cinerea in response to bacteria.The ISME journal · 2019Article
- Microfluidics and Metabolomics Reveal Symbiotic Bacterial-Fungal Interactions BetweenFrontiers in microbiology · 2019Article
- Transcriptomics Analysis of the Chinese Pear Pathotype ofInternational journal of molecular sciences · 2018Article
- Transcriptional and Antagonistic Responses of Biocontrol StrainFrontiers in microbiology · 2017Article
- Transcriptomic responses of a simplified soil microcosm to a plant pathogen and its biocontrol agent reveal a complex reaction to harsh habitat.BMC genomics · 2016Article
- Fungal Innate Immunity Induced by Bacterial Microbe-Associated Molecular Patterns (MAMPs).G3 (Bethesda, Md.) · 2016Article
- Magnaporthe oryzae effectors MoHEG13 and MoHEG16 interfere with host infection and MoHEG13 counteracts cell death caused by Magnaporthe-NLPs in tobacco.Plant cell reports · 2016Article
- Identification of a Novel Nematotoxic Protein by Challenging the Model Mushroom Coprinopsis cinerea with a Fungivorous Nematode.G3 (Bethesda, Md.) · 2015Article
- Over-Expression of Rice CBS Domain Containing Protein, OsCBSX3, Confers Rice Resistance to Magnaporthe oryzae Inoculation.International journal of molecular sciences · 2015Article
- Transcriptomic analysis reveals new regulatory roles of Clp signaling in secondary metabolite biosynthesis and surface motility in Lysobacter enzymogenes OH11.Applied microbiology and biotechnology · 2014Article
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plants and animals have evolved a first line of defense response to pathogens called innate or basal immunity. While basal defenses in these organisms are well studied, there is almost a complete lack of understanding of such systems in fungal species, and more specifically, how they are able to detect and mount a defense response upon pathogen attack. Hence, the goal of the present study was to understand how fungi respond to biotic stress by assessing the transcriptional profile of the rice blast pathogen, Magnaporthe oryzae, when challenged with the bacterial antagonist Lysobacter enzymogenes. Based on microscopic observations of interactions between M. oryzae and wild-type L. enzymogenes strain C3, we selected early and intermediate stages represented by time-points of 3 and 9 hours post-inoculation, respectively, to evaluate the fungal transcriptome using RNA-seq. For comparative purposes, we also challenged the fungus with L. enzymogenes mutant strain DCA, previously demonstrated to be devoid of antifungal activity. A comparison of transcriptional data from fungal interactions with the wild-type bacterial strain C3 and the mutant strain DCA revealed 463 fungal genes that were down-regulated during attack by C3; of these genes, 100 were also found to be up-regulated during the interaction with DCA. Functional categorization of genes in this suite included those with roles in carbohydrate metabolism, cellular transport and stress response. One gene in this suite belongs to the CFEM-domain class of fungal proteins. Another CFEM class protein called PTH11 has been previously characterized, and we found that a deletion in this gene caused advanced lesion development by C3 compared to its growth on the wild-type fungus. We discuss the characterization of this suite of 100 genes with respect to their role in the fungal defense response.
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