ReviewFrontiers in human neuroscience2013
Imaging structural and functional brain networks in temporal lobe epilepsy.
Review in Frontiers in human neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers, 1 of them a synthesis that pooled it.
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Who cites it
118 citing papers in PubMed, 1 synthesis or guideline pooled it, 233 citations in OpenAlex.
- Pooled it
- Interpretable Multiscale Directed Temporal Graph Learning for MEG-Based Identification and Lateralization of Temporal Lobe Epilepsy.Sensors (Basel, Switzerland) · 2026Article
- Integrating multivariate resting-state fMRI features to localize epileptic networks in common childhood epilepsy.Epilepsia · 2026Article
- Contralateral language network integration predicts and protects against naming decline after temporal lobe resection.Epilepsia · 2026Article
- Review
- Abnormal functional connectivity patterns in temporal lobe epilepsy-An international ENIGMA-epilepsy study.Epilepsia open · 2026Article
- Long-term predictors of seizure outcome after anterior temporal lobectomy in unilateral hippocampal sclerosis: A 281-patient cohort with mean 10-year follow-up.Epileptic disorders : international epilepsy journal with videotape · 2026Article
- The synaptic organization of the human temporal lobe neocortex by high-resolution transmission, focused ion beam scanning, and electron microscopic tomography.Anatomical science international · 2025Review
- Elevated neuroinflammation and region-specific clinical correlates in drug-resistant focal epilepsy.Seizure · 2025Article
- Geometric representations of brain networks can predict the surgery outcome in temporal lobe epilepsy.NPJ systems biology and applications · 2025Article
- Alterations of Activity in Visual Areas of Left Mesial Temporal Lobe Epilepsy Patients: Evidence from Moving Facial Emotional Tasks.Annals of neurosciences · 2025Article
- Identification of topological alterations using microstate dynamics in patients with infantile epileptic spasms syndrome.Scientific reports · 2025Article
- Disrupted modular and hub topology in right temporal lobe epilepsy: a multimodal MRI network analysis.Frontiers in neurology · 2025Article
- Sleep links hippocampal propensity for epileptiform activity to its viscerosensory inputs.Frontiers in neuroscience · 2025Article
- Differential reorganization of episodic and semantic memory systems in epilepsy-related mesiotemporal pathology.Brain : a journal of neurology · 2024Article
- Olfactory Dysfunction and Limbic Hypoactivation in Temporal Lobe Epilepsy.Human brain mapping · 2024Article
- Edge-wise analysis reveals white matter connectivity associated with focal to bilateral tonic-clonic seizures.Epilepsia · 2024Article
- Connectome-Based Neurosurgery in Primary Intra-Axial Neoplasms: Beyond the Traditional Modular Conception of Brain Architecture for the Preservation of Major Neurological Domains and Higher-Order Cognitive Functions.Life (Basel, Switzerland) · 2024Review
- Altered functional connectivity after pilocarpine-induced seizures revealed by intrinsic optical signals imaging in awake mice.Neurophotonics · 2024Article
- Topological regularization of networks in temporal lobe epilepsy: a structural MRI study.Frontiers in neuroscience · 2024Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early imaging studies in temporal lobe epilepsy (TLE) focused on the search for mesial temporal sclerosis, as its surgical removal results in clinically meaningful improvement in about 70% of patients. Nevertheless, a considerable subgroup of patients continues to suffer from post-operative seizures. Although the reasons for surgical failure are not fully understood, electrophysiological and imaging data suggest that anomalies extending beyond the temporal lobe may have negative impact on outcome. This hypothesis has revived the concept of human epilepsy as a disorder of distributed brain networks. Recent methodological advances in non-invasive neuroimaging have led to quantify structural and functional networks in vivo. While structural networks can be inferred from diffusion MRI tractography and inter-regional covariance patterns of structural measures such as cortical thickness, functional connectivity is generally computed based on statistical dependencies of neurophysiological time-series, measured through functional MRI or electroencephalographic techniques. This review considers the application of advanced analytical methods in structural and functional connectivity analyses in TLE. We will specifically highlight findings from graph-theoretical analysis that allow assessing the topological organization of brain networks. These studies have provided compelling evidence that TLE is a system disorder with profound alterations in local and distributed networks. In addition, there is emerging evidence for the utility of network properties as clinical diagnostic markers. Nowadays, a network perspective is considered to be essential to the understanding of the development, progression, and management of epilepsy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.