ArticlePLoS pathogens2013
Type I J-domain NbMIP1 proteins are required for both Tobacco mosaic virus infection and plant innate immunity.
Article in PLoS pathogens, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 64 citations in OpenAlex.
- A viral protein diverts the endocytic VPS9a-Rab5 pathway to promote virus infection in plants.Science advances · 2026Article
- Small heat shock and J-domain proteins direct defense against areca palm velarivirus 1 by degrading coat protein via autophagy.Nature communications · 2026Article
- Deciphering cassava brown streak virus infection in cassava through VPg mediated host protein interactions.Archives of virology · 2026Article
- Tomato Brown Rugose Fruit Virus Evades Tm-2Molecular plant pathology · 2026Article
- Transcriptomic responses of beet to infection by beet mild yellowing virus.BMC plant biology · 2025Article
- Association of the tomato co-chaperone geneHorticulture research · 2025Article
- A pentatomomorpha-specific salivary protein activates plant immunity and is critical for insect feeding.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Tobacco Mosaic Virus Movement: From Capsid Disassembly to Transport Through Plasmodesmata.Viruses · 2025Review
- Next-generation mapping of the salicylic acid signaling hub and transcriptional cascade.Molecular plant · 2024Article
- Plant Immunity against Tobamoviruses.Viruses · 2024Review
- Next-generation mapping of the salicylic acid signaling hub and transcriptional cascade.bioRxiv : the preprint server for biology · 2024Article
- Verification of the Interaction Target Protein of the Effector ApCE22 ofBiomolecules · 2023Article
- Characterization of a ToMV isolate overcoming Tm-2Virus genes · 2022Article
- Bioinformatic-based approach for mutagenesis of plant immune Tm-2Frontiers in plant science · 2022Article
- Turnip mosaic virus P1 suppresses JA biosynthesis by degrading cpSRP54 that delivers AOCs onto the thylakoid membrane to facilitate viral infection.PLoS pathogens · 2021Article
- Identification of genetic determinants of tomato brown rugose fruit virus that enable infection of plants harbouring the Tm-2Molecular plant pathology · 2021Article
- Review
- EDS1-interacting J protein 1 is an essential negative regulator of plant innate immunity in Arabidopsis.The Plant cell · 2021Article
- The unfolded protein response plays dual roles in rice stripe virus infection through fine-tuning the movement protein accumulation.PLoS pathogens · 2021Article
- DnaJ Proteins RegulatePlants (Basel, Switzerland) · 2021Article
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Authors and funding
11 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tm-2² is a coiled coil-nucleotide binding-leucine rich repeat resistance protein that confers durable extreme resistance against Tomato mosaic virus (ToMV) and Tobacco mosaic virus (TMV) by recognizing the viral movement protein (MP). Here we report that the Nicotiana benthamiana J-domain MIP1 proteins (NbMIP1s) associate with tobamovirus MP, Tm-2² and SGT1. Silencing of NbMIP1s reduced TMV movement and compromised Tm-2²-mediated resistance against TMV and ToMV. Furthermore, silencing of NbMIP1s reduced the steady-state protein levels of ToMV MP and Tm-2². Moreover, NbMIP1s are required for plant resistance induced by other R genes and the nonhost pathogen Pseudomonas syringae pv. tomato (Pst) DC3000. In addition, we found that SGT1 associates with Tm-2² and is required for Tm-2²-mediated resistance against TMV. These results suggest that NbMIP1s function as co-chaperones during virus infection and plant immunity.
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