ReviewClinicoEconomics and outcomes research : CEOR2013
Cost of noninfectious comorbidities in patients with HIV.
Review in ClinicoEconomics and outcomes research : CEOR, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Changes in multimorbidity burden and their impact on patient and healthcare outcomes in people with HIV over a 3-5-year period.AIDS (London, England) · 2025Article
- National Evaluation of HIV Service Resource Allocation in Tanzania.AIDS and behavior · 2023Article
- Determinants of Direct Costs of HIV-1 Outpatient Care in Israel.International journal of environmental research and public health · 2022Article
- Article
- Trends in Comorbidities Among Human Immunodeficiency Virus-Infected Hospital Admissions in New York City from 2006-2016.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- The Lymph Node Reservoir: Physiology, HIV Infection, and Antiretroviral Therapy.Clinical pharmacology and therapeutics · 2021Review
- Comorbidities and HCV coinfection in the management of HIV+ patients: evidence from the Italian clinical practice.Health economics review · 2020Article
- Use of Bisphosphonates, Calcium and Vitamin D for Bone Demineralization in Patients with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome: A Systematic Review and Meta-Analysis of Clinical Trials.Journal of bone metabolism · 2020Article
- Comorbidities in people living with HIV: An epidemiologic and economic analysis using a claims database in France.PloS one · 2020Article
- Frequency of non-communicable diseases in people 50 years of age and older receiving HIV care in Latin America.PloS one · 2020Article
- Association between HIV infection and outcomes of care among medicare enrollees with breast cancer.EClinicalMedicine · 2019Article
- Chronic multimorbidity among older adults in rural South Africa.BMJ global health · 2019Article
- The Importance of Improving the Quality of Care Among HIV/AIDS Hospitalizations in Portugal.Frontiers in public health · 2019Article
- A profile of adult acute admissions to Lentegeur Psychiatric Hospital, South Africa.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2019Article
- Comorbidities and costs in HIV patients: A retrospective claims database analysis in Germany.PloS one · 2019Article
- Multimorbidity and care for hypertension, diabetes and HIV among older adults in rural South Africa.Bulletin of the World Health Organization · 2019Article
- Impact of comorbidity on the risk and cost of hospitalization in HIV-infected patients: real-world data from Abruzzo Region.ClinicoEconomics and outcomes research : CEOR · 2018Article
- A Population-Based Study of Care at the End of Life Among People With HIV in Ontario From 2010 to 2013.Journal of acquired immune deficiency syndromes (1999) · 2017Article
- Late presentation increases risk and costs of non-infectious comorbidities in people with HIV: an Italian cost impact study.AIDS research and therapy · 2017Article
- Global Shifts in Cardiovascular Disease, the Epidemiologic Transition, and Other Contributing Factors: Toward a New Practice of Global Health Cardiology.Cardiology clinics · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe hypothesized that the increased prevalence of noninfectious comorbidities (NICMs) observed among HIV-infected patients may result in increased direct costs of medical care compared to the general population. Our objective was to provide estimates of and describe factors contributing to direct costs for medical care among HIV-infected patients, focusing on NICM care expenditure.
methodsA case-control study analyzing direct medical care costs in 2009. Antiretroviral therapy (ART)-experienced HIV-infected patients (cases) were compared to age, sex, and race-matched adults from the general population, included in the CINECA ARNO database (controls). NICMs evaluated included cardiovascular disease, hypertension, diabetes mellitus, bone fractures, and renal failure. Medical care cost information evaluated included pharmacy, outpatient, and inpatient hospital expenditures. Linear regression models were constructed to evaluate predictors of total care cost for the controls and cases.
resultsThere were 2854 cases and 8562 controls. Mean age was 46 years and 37% were women. We analyzed data from 29,275 drug prescription records. Positive predictors of health care cost in the overall population: HIV infection (β = 2878; confidence interval (CI) = 2001-3755); polypathology (β = 8911; CI = 8356-9466); age (β = 62; CI = 45-79); and ART exposure (β = 18,773; CI = 17,873-19,672). Predictors of health care cost among cases: Center for Disease Control group C (β = 1548; CI = 330-2766); polypathology (β = 11,081; CI = 9447-12,716); age < 50 years (β = 1903; CI = 542-3264); protease inhibitor exposure (per month of use; β = 69; CI = 53-85); CD4 count < 200 cells/mm(3) (β = 5438; CI = 3082-7795); and ART drug change (per change; β = 911; CI = 716-1106).
conclusionTotal cost of medical care is higher in cases than controls. Lower medical costs associated with higher CD4 strata are offset by increases in the care costs needed for advancing age, particularly for NICMs.
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