Evidence map›Paper›PMID 24097298›Full record

ArticleInternational journal of obesity (2005)2014

The association of birth order with later body mass index and blood pressure: a comparison between prospective cohort studies from the United Kingdom and Brazil.

L D Howe, P C Hallal, A Matijasevich, J C Wells, I S Santos, A J D Barros, D A Lawlor, C G Victora, G D Smith

Abstract readMulticenter Study
In one paragraph

Article in International journal of obesity (2005), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

L D Howe1] MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK [2] School of Social and Community Medicine, University of Bristol, Bristol, UK.
P C HallalPostgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.
A MatijasevichPostgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.
J C WellsInstitute of Child Health, University College London, London, UK.
I S SantosPostgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.
A J D BarrosPostgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.
D A Lawlor1] MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK [2] School of Social and Community Medicine, University of Bristol, Bristol, UK.
C G VictoraPostgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.
G D Smith1] MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK [2] School of Social and Community Medicine, University of Bristol, Bristol, UK.

Funding

Medical Research Council G1002375Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_UU_12013/1Medical Research Council MC_UU_12013/5Wellcome Trust 086974Wellcome Trust 092731Wellcome Trust 102215
6 · The paper itself

Abstract

backgroundPrevious studies have found greater adiposity and cardiovascular risk in first born children. The causality of this association is not clear. Examining the association in diverse populations may lead to improved insight.

methodsWe examine the association between birth order and body mass index (BMI), systolic and diastolic blood pressure (SBP/DBP) in the 2004 Pelotas cohort from southern Brazil and the Avon Longitudinal Study of Parents and Children (ALSPAC) from Bristol, south-west England, restricting analysis to families with two children in order to remove confounding by family size.

resultsNo consistent differences in BMI, SBP or DBP were observed comparing first and second born children. Within the Pelotas 2004 cohort, first born females were thinner, with lower SBP and DBP; for example, mean difference in SBP comparing first with second born was -0.979 (95% confidence interval -2.901 to 0.943). In ALSPAC, first born females had higher BMI, SBP and DBP. In both cohorts, associations tended to be in the opposite direction in males, although no statistical evidence for gender interactions was found.

conclusionsThe findings do not support an association between birth order and BMI or blood pressure. Differences to previous studies may be explained by differences in populations and/or confounding by family size in previous studies.

Indexed as

AdiposityBirth WeightAdolescentAdultAge FactorsBirth OrderBlood PressureBody HeightBody Mass IndexBrazilCardiovascular DiseasesChildFamily CharacteristicsFemaleFollow-Up StudiesHumans

Identifiers

PMID24097298
PMCPMC4024316

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.