Evidence map›Paper›PMID 24097121›Full record

ArticleEye (London, England)2014

Influence of cataract maturity on aqueous humor lipid peroxidation markers and antioxidant enzymes.

D J Miric, B M Kisic, L D Zoric, B M Miric, M Mirkovic, R Mitic

Open access · bronzeAbstract read
In one paragraph

Article in Eye (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

D J MiricInstitute of Biochemistry, Medical Faculty Pristina, Kosovska Mitrovica, Serbia.
B M KisicInstitute of Biochemistry, Medical Faculty Pristina, Kosovska Mitrovica, Serbia.
L D ZoricEye Disease Clinic, Medical Faculty Pristina, Kosovska Mitrovica, Serbia.
B M MiricDepartment of Informatics, State University of Novi Pazar, Novi Pazar, Serbia.
M MirkovicEye Disease Clinic, Medical Faculty Pristina, Kosovska Mitrovica, Serbia.
R MiticInstitute of Pharmacology, Medical Faculty Pristina, Kosovska Mitrovica, Serbia.
University Hospital Medical Center Bezanijska kosa · RSState University of Novi Pazar · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe impact of cataract maturity on the aqueous humor (AH) oxidant/antioxidant balance is largely controversial. This study was aimed at assessing the relationships between cataract maturity and AH lipid peroxidation markers and enzymatic antioxidants. PATIENTS AND

methodsThe concentrations of conjugated dienes (CD), lipofuscin-like fluorescent end-products (LLF), soluble proteins, as well as the activities of superoxide dismutase (SOD) and catalase (CAT) were measured in AH samples from nondiabetic patients with either immature (n=15) or mature (n=15) cataract.

resultsIn the overall AH sample, the mean values of CD, LLF, SOD, and CAT were 0.160 ± 0.024 (OD234), 166 ± 27 RFU, 24.5 ± 7.1 U/ml, and 31.9 ± 3.9 pmol/ml, respectively. CD was positively correlated with SOD (r=0.647; P<0.001), CAT (r=-0.394; P=0.031), and LLF (r=-0.399; P=0.029). The LLF was negatively correlated with SOD (r=-0.461; P=0.010). In samples adjusted for confounding factors, differences between immature and mature cataract groups regarding SOD, CD, LLF, and total proteins were significant (P<0.05; for all variables). The multiple logistic regression analysis identified LLF (OR=4.08; P=0.038) and SOD (OR=4.99; P=0.031) as independent predictors of cataract maturity.

conclusionsThese results suggest that AH lipid peroxidation markers and antioxidants may significantly depend on the cataract maturity stage.

Indexed as

Lipid PeroxidationAgedAged, 80 and overAgingAntioxidantsAqueous HumorBiomarkersCatalaseCataractFemaleHumansLipid PeroxidesLipofuscinMaleMiddle AgedOxidation-ReductionAntioxidantsBiomarkersCatalaseCAT protein, humanLipid PeroxidesLipofuscinSuperoxide Dismutase

Identifiers

PMID24097121
PMCPMC3890749
OpenAlexW2085408409

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.